Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik

Permanent URI for this collectionhttps://hdl.handle.net/11147/9

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Author: search.filters.author.Bayraktar, Oğuz

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  • Conference Object
    Citation - WoS: 2
    Incorporation of Equisetum Arvense Extract Into Silk Fibroin-Hyaluronic Acid Sponge Matrices for Wound Dressing Applications
    (Elsevier, 2012) Uslu, Mehmet Emin; Erdoğan, İpek; Bayraktar, Oğuz
    Equisetum arvense extract has frequently been investigated for its antioxidant capacity, antimicrobial and antitumor properties. However, one of the challenges in natural compound investi-gations is to maintain the stability of polyphenolic compounds during their storage and applications. For this purpose extracts can be incorporated into different forms of biomaterial. In this research silk fibroin (SF) and hyaluronic acid (HA) was used as sponge matri-ces for wound dressing application.
  • Book Part
    Citation - WoS: 30
    Citation - Scopus: 41
    Nanocarriers for Plant-Derived Natural Compounds
    (Elsevier Ltd., 2017) Bayraktar, Oğuz; Erdoğan, İpek; Köse, Merve D.; Kalmaz, Gülcan
    Natural products constitute a large fraction in drug discovery processes. The term includes compounds from plants, microorganisms, and animals. Most of the natural products are secondary metabolites derived from plants, which are low in amounts and difficult to isolate. Another issue is the preservation of their bioactivity during process and storage as well as degradation in the gastrointestinal system before reaching circulation. Advances in nanotechnology offer nanoparticles, nanocapsules, and conjugates, which are devoted to site-specific, time-controlled delivery of bioactive agents. Nanoencapsulated systems have the advantage of high drug encapsulation efficiency because of optimized drug solubility in the core, low polymer content compared to other nanoparticulated systems such as nanospheres, drug polymeric shell protection against degradation factors, and the reduction of tissue irritation caused by the polymeric shell. This chapter will discuss nanoencapsulation methods and advances in carrier systems for plant-derived natural compounds.