Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik

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Author: search.filters.author.Dinçer İşoğlu, SevilScopus Q: search.filters.scopusQuartile.Q1

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    Advantage of Co-Culture Strategy for Targeted Cancer Treatment and in Vitro Studies
    (Elsevier, 2021) Ulu, Gizem Tuğçe; Bayram, Nazende Nur; Dinçer İşoğlu, Sevil; Baran, Yusuf
    Breast cancer tissues include carcinoma cells and stromal cells, and intra-tumoral stroma that consists of different types of cells. For this point, cell-cell interaction and communication have a potential role in cancer progression. Mono-cell culture is used for cancer treatment approaches. However, cell-cell interaction and communication can not be evaluated on mono-culture cells. So, co-culture models provide low-cost screening to determine cell proliferation for drug application before moving forward to in vivo models. Also, determination of cell morphology in co culture system is critical to understand advantages.