Bioengineering / Biyomühendislik

Permanent URI for this collectionhttps://hdl.handle.net/11147/4529

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Author: search.filters.author.Arslan Yıldız, AhuSubject: search.filters.subject.3D bioprinting

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  • Book Part
    Citation - Scopus: 2
    Bioprinting of Hydrogels for Tissue Engineering and Drug Screening Applications
    (Elsevier, 2022) Özmen, Ece; Arslan Yıldız, Ahu; Yıldırım, Özüm; Arslan Yıldız, Ahu; 03.01. Department of Bioengineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
    In tissue engineering, the 3-dimensional (3D) bioprinting method that enables the production of 3D structures by combining bioinks and cells has become one of the most promising technique. Over the last few years, 3D cell culture models gained importance in the development of disease model and drug development studies. The successful production of the 3D structures by 3D bioprinting mostly depends on the properties of the bioink to be used. Hydrogels, which are natural or synthetic polymers, are generally preferred as bioink materials with their high swelling ability, biocompatibility, biodegradability, and easy gelation ability. The convenience of hydrogels for varied bioprinting applications make them proper bioink materials for bioprinting of artificial tissues, tumor models, and tissue grafts. Bioprinting of functional tissues is successfully performed for years, and hydrogels are utilized as bioink in bone, vascular, neural, cartilage, cardiac, skin tissue engineering, and drug screening. In this chapter, bioprinting methodology, bioinks, hydrogel bioinks, and their applications are discussed in detail. © 2023 Elsevier Inc. All rights reserved.
  • Conference Object
    Development of New Generation Hydrocolloid Bio-Ink for 3d Bioprinting
    (Mary Ann Liebert, 2022) Arslan Yıldız, Ahu; 03.01. Department of Bioengineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
    Bioprinting enables the production of 3-dimensional (3D) structures by combining bioinks, living cells, extracellular matrix (ECM) components, biochemical factors, proteins, drugs; and it has recently become one of the most promising techniques in the field of tissue engineering. The successful production of the 3D structure to be created by 3D bioprinting technology depends on the properties of the bio-ink to be used. Hydrogel/hydrocolloid materials used as bio-inks are developed using synthetic and natural polymers where they have the necessary rheological properties for printing, they also have biocompatibility, low toxicity and support for cell attachment. Natural hydrogels, which have the ability to mimic the extracellular matrix structure and function at a high rate, are highly preferred bioink materials for bioprinting applications.