Bioengineering / Biyomühendislik

Permanent URI for this collectionhttps://hdl.handle.net/11147/4529

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Institution Author: search.filters.institutionAuthor.Küçüksolak, MelisPublisher: search.filters.publisher.Georg Thieme Verlag

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  • Conference Object
    Induction of Secondary Metabolism of Marine Derived Streptomyces Cacaoi
    (Georg Thieme Verlag, 2019) Gezer, Erkin; Küçüksolak, Melis; Bilgi, Eyüp; Bedir, Erdal; Küçüksolak, Melis; Bilgi, Eyüp; Bedir, Erdal; 03.01. Department of Bioengineering; 03. Faculty of Engineering; 01. Izmir Institute of Technology
    Microbial natural products have an adaptive role as signal molecules or defense tools in ecological interactions. Biosynthesis of these molecules is suppressed in standard laboratory conditions where there are no ecological triggers. Thus, only a portion of the chemical diversity of a microbial strain is discovered by standard fermentation protocols. However, using different fermentation conditions or different approaches such as co-culture, biosynthesis of these suppressed molecules can be triggered, and new natural products can be isolated.
  • Conference Object
    Citation - WoS: 1
    Telomerase Activators Derived From Astragalus Sapogenins Via Biotransformation With the Recently Discovered Endophytic Fungus Camarosporium Laburnicola
    (Georg Thieme Verlag, 2019) Küçüksolak, Melis; Yılmaz, Sinem; Ekiz, Güner; Duman, Seda; Duman, Seda; Bedir, Erdal; Yılmaz, Sinem; Küçüksolak, Melis; Ballar Kırmızıbayrak, Petek; Bedir, Erdal; 03.01. Department of Bioengineering; 01.01. Units Affiliated to the Rectorate; 01. Izmir Institute of Technology; 03. Faculty of Engineering
    Telomeres are nucleotide sequences that are located at the end of chromosomes shortening with each cell division. Telomerase is a reverse transcriptase enzyme, and it helps to replenish telomere ends that are truncated by aging and stress factors.