Bioengineering / Biyomühendislik

Permanent URI for this collectionhttps://hdl.handle.net/11147/4529

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Institution Author: search.filters.institutionAuthor.Yetgin, Ali

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  • Article
    Pterigynandrum Filiforme Hedw. Türünün Antimikrobiyal Aktivitesinin Belirlenmesi
    (Çankırı Karatekin Üniversitesi, 2017) Yetgin, Ali; Şenturan, Merve; Benek, Atakan; Efe, Ebru; Canlı, Kerem
    Pterigynandrum filiforme Hedw. Orta Avrupa ve Anadolu’nun dağlık alanlarında orman altlarında yaşayan bir karayosunu türüdür. Yayılış alanı geniş olduğu için bulunması kolaydır. Antimikrobiyal çalışmaların amacı dünya üzerinde enfeksiyon hastalıklarına sebep olan mikroorganizmaların etkilerini yok edebilen maddelerin bulunmasıdır. Yapılan antimikrobiyal aktivite çalışmasıyla P. filiforme’nin 17 bakteri ve 1 maya türü üzerindeki etkisi analiz edildi. Etanol ekstraksiyon yöntemi ile 0.27 ve 0.93 mg örnekler hazırlandı ve disk difüzyon yöntemi ile geniş spektrumlu antimikrobiyal analizi yapıldı. P. filiforme karayosununun antimikrobiyal potansiyeli konusunda literatürde herhangi bir araştırma bulunmamaktadır. P. filiforme örnekleri ile çalışılan bakterilerde antimikrobiyal etki belirlenmiştir. Bunlar gram pozitif bakteriler olan S. aureus, B. subtilis, L. monocytogenes ve E. faecalis; gram negatif bakteriler olan K. pneumoniae ve S. enteritidis olmaktadır.
  • Article
    Citation - WoS: 14
    Citation - Scopus: 12
    Determination of the Chemical Composition and Antimicrobial Activity of Frankenia Hirsuta
    (Bangladesh Pharmacological Society, 2017) Canlı, Kerem; Şimşek, Özcan; Yetgin, Ali; Altuner, Ergin Murat
    Frankenia hirsuta is widely located in Turkey, but the antimicrobial potential and biochemical composition analysis of it weren't determined yet. By using the disk diffusion method, the susceptibility of 17 bacteria and 1 fungi were analyzed, which included Bacillus, Candida, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella and Staphylococcus genera. 0.8, 1.5 and 3.1 mg of samples were prepared by using absolute ethanol. The bioactive composition of the plant extract was determined by gas chromatography-mass spectroscopy, and National Institute of Standards and Technology library was used for the mass spectra analysis. The results showed that F. hirsuta had antimicrobial activity against all of the studied micro-organisms except E. aerogenes and E. coli. Several active metabolites were identified, but some composition of this sample didn't match with the library. These results are the first report for the antimicrobial potential and biochemical composition of F. hirsuta.
  • Article
    Citation - WoS: 14
    Citation - Scopus: 18
    Comparison of Antimicrobial Activity of Allium Sativum Cloves From China and Taskopru, Turkey
    (Hindawi Publishing Corporation, 2018) Yetgin, Ali; Canlı, Kerem; Altuner, Ergin Murat
    In this study, antimicrobial activities of two different samples of Allium sativum L. from Turkey (TR) (Taskopru, Kastamonu, Turkey) and China (CN) were determined. A broad spectrum of Gram-negative and Gram-positive bacteria (17 bacteria) including species of Bacillus, Enterobacter, Enterococcus, Escherichia, Klebsiella, Listeria, Pseudomonas, Salmonella, and Staphylococcus were used for testing antibacterial activity. In addition, antifungal activity against Candida albicans was also investigated. Antimicrobial activity was tested by using 3 different processes (chopping, freezing, and slicing by the disk diffusion method). The results showed that TR garlic presented more antimicrobial activity than CN garlic. Mechanism of activity of CN garlic could be proposed to be different from that of TR garlic.