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Development of Novel Nanotoxicity Assessment Method Utilizing 3d Printing System
(Elsevier, 2022) Başlar, Muhammet Semih; Öksel Karakuş, Ceyda; Aldemir Dikici, Betül
Unique physicochemical properties of nanomaterials (NMs) make them a material of choice in various applications but also raise concerns about their potential toxicity. While the commercial use of nano-enabled materials is growing rapidly, their interaction with biological systems and environment are not yet fully understood [1, 2]. Traditionally, toxicity of nano-sized materials are assessed by 2D cell culture models due to their time and cost-related advantages but their simplicity often comes at the cost of accuracy. While these methods are considered as the first step in toxicological assessment of both nanosized and bulk-form materials, they fall short in mimicking the complexity of in vivo physiological environments.

Bioengineering / Biyomühendislik