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Citation - WoS: 1
Telomerase Activators Derived From Astragalus Sapogenins Via Biotransformation With the Recently Discovered Endophytic Fungus Camarosporium Laburnicola
(Georg Thieme Verlag, 2019) Küçüksolak, Melis; Ekiz, Güner; Duman, Seda; Yılmaz, Sinem; Ballar Kırmızıbayrak, Petek; Bedir, Erdal
Telomeres are nucleotide sequences that are located at the end of chromosomes shortening with each cell division. Telomerase is a reverse transcriptase enzyme, and it helps to replenish telomere ends that are truncated by aging and stress factors.
Citation - WoS: 7
Citation - Scopus: 7
Flavonol Glycosides From Reseda Lutea L
(Elsevier Ltd., 2019) Kızıltaş, Hatice; Küçüksolak, Melis; Duman, Seda; Bedir, Erdal
Two new flavonol glycosides; kaempferol-3-O-[2-O-(beta-D-xylopyranosyl)-3-O-(beta-D-glucopyranosyl)]-alpha-L-rhamnopyranosyl-7-O-alpha-L-rhamnopyranoside (1) and kaempferol-3-O-[2-O-((6-O-trans-p-coumaryl)-beta-D-glucopyranosyl)-3-O-(beta-D-xylopyranosyl)]-alpha-L-rhamnopyranosyl-7-O-alpha-L-rhamnopyranoside (2) were isolated from the aerial parts of Reseda lutea L., together with five known flavonol glycosides. Structural elucidation of the compounds was based on both spectroscopic evidence and reference data comparison. The new compounds are the first tetrasaccharidic secondary metabolites isolated from Resedaceae family.

Bioengineering / Biyomühendislik