Bioengineering / Biyomühendislik

Permanent URI for this collectionhttps://hdl.handle.net/11147/4529

Browse

Filters

20201

Settings

Publisher: search.filters.publisher.SAGE PublicationsSubject: search.filters.subject.Bone filling material

Search Results

Now showing 1 - 1 of 1
  • Article
    Citation - WoS: 12
    Citation - Scopus: 17
    Fish Scale/Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) Nanofibrous Composite Scaffolds for Bone Regeneration
    (SAGE Publications, 2020) Kara, Aylin; Güneş, Oylum C.; Albayrak, Aylin Z.; Bilici, Gökçen; Erbil, Güven; Havitcioğlu, Hasan
    The aim of this study was to produce three-dimensional, nanofibrous fish scale/poly(3-hydroxybutyrate-co-3-hydroxyvalerate) composite scaffolds as bone filling materials. This is the first report wherein fish scales were used within a nanofibrous matrix for bone regeneration. Composite scaffolds with a cotton wool-like structure (fiber diameter: 560 +/- 64 nm; porosity: 82%) were obtained by incorporating chopped fish scales into wet-electrospun poly(3-hydroxybutyrate-co-3-hydroxyvalerate) nanofibers and freeze-drying. The addition of the fish scales improved the mechanical properties, biomineralization tendency, cell viability, alkaline phosphatase activity, and type I collagen production. Consequently, produced composite scaffolds would be regarded to have the therapeutic capacity in bone tissue damages.