PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
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Article Citation - WoS: 15Citation - Scopus: 18Search for Supersymmetry in pp Collisions at √s=13 TeV in the Single-Lepton Final State Using the Sum of Masses of Large-Radius Jets(Amer Physical Soc, 2017) Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Ambrogi, F.; Asilar, E.; Bergauer, T.; Woods, N.Results are reported from a search for supersymmetric particles in proton-proton collisions in the final state with a single lepton, multiple jets, including at least one b-tagged jet, and large missing transverse momentum. The search uses a sample of proton-proton collision data at root s = 13 TeV recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 35.9 fb(-1). The observed event yields in the signal regions are consistent with those expected from standard model backgrounds. The results are interpreted in the context of simplified models of supersymmetry involving gluino pair production, with gluino decay into either on- or off-mass-shell top squarks. Assuming that the top squarks decay into a top quark plus a stable, weakly interacting neutralino, scenarios with gluino masses up to about 1.9 TeV are excluded at 95% confidence level for neutralino masses up to about 1 TeV.Article Citation - Scopus: 34Machine Learning Methods for Microrna Gene Prediction(Humana Press Inc., 2014) Saçar,M.D.; Allmer,J.MicroRNAs (miRNAs) are single-stranded, small, noncoding RNAs of about 22 nucleotides in length, which control gene expression at the posttranscriptional level through translational inhibition, degradation, adenylation, or destabilization of their target mRNAs. Although hundreds of miRNAs have been identified in various species, many more may still remain unknown. Therefore, discovery of new miRNA genes is an important step for understanding miRNA-mediated posttranscriptional regulation mechanisms. It seems that biological approaches to identify miRNA genes might be limited in their ability to detect rare miRNAs and are further limited to the tissues examined and the developmental stage of the organism under examination. These limitations have led to the development of sophisticated computational approaches attempting to identify possible miRNAs in silico. In this chapter, we discuss computational problems in miRNA prediction studies and review some of the many machine learning methods that have been tried to address the issues. © Springer Science+Business Media New York 2014.Article Citation - WoS: 139Granulocytic Sarcoma: a Systematic Review(e-Century Publishing Corporation, 2013) Yılmaz, Asu Fergün; Saydam, Güray; Şahin, Fahri; Baran, YusufGranulocytic sarcoma also called myeloid sarcoma is an extramedullary tumor of immature granulocytic cells. It is a rare entity, and mostly accompanied by acute myeloid leukemia. It is observed during the course of myeloproliferative disorders especially in chronic myeloid leukemia and myelodysplastic syndromes. In some rare circumstances, it is detected before clinical signs of leukemia or other diseases. When the bone marrow biopsy reveals no other hematologic malignancies, the granulocytic sarcoma is described as nonleukemic, primary or isolated. It is observed at any part of the body but the most common locations are soft tissues, bone, peritoneum and lymph nodes. Presenting signs or symptoms are mainly due to mass effect of the tumor and dysfunction of the organ, or the tissue that is affected. The diagnosis is performed by biopsy of the tumor. The tumor consists of immature granulocytic cells, which could be documented by H&E, immunohistochemistry, and flow cytometric methods. Fluorescence in-situ hybridization and molecular analysis are also performed. The optimal time and type of treatment is not clear. Surgery could be an option especially for tumors, which cause organ dysfunction and/or obstruction. Systemic treatment should be considered in all patients because without systemic treatment, relapses and progression to acute myeloid leukemia is the ultimate fate of the disease in many cases. Cytarabine-containing remission-induction chemotherapies have been the most applied therapeutic strategies, but it is not clear whether the consolidation therapies are required or not, and what kind of regimens are appropriate. The role of hematopoietic stem cell transplantation (HSC) as a consolidation regimen is not clear, but, after the relapse of the disease with or without bone marrow involvement, HSC transplantation should be considered in suitable patients after the reinduction performed by AML chemotherapies. There is only limited data about the role of radiotherapy in these patients. It could be used in patients with relapsed disease, organ dysfunction which should be quickly relieved and inadequate response to chemotherapy. The effect of radiotherapy on overall survival is not known. New prospective studies and clinical trials are needed to generate guidelines for the treatment of primary granulocytic sarcomas.Data Paper Citation - WoS: 3Citation - Scopus: 4Experimental data showing the thermal behavior of a flat roof with phase change material(Elsevier, 2015) Tokuç, Ayça; Başaran, Tahsin; Yesügey, Sadık CengizThe selection and configuration of building materials for optimal energy efficiency in a building require some assumptions and models for the thermal behavior of the utilized materials. Although the models for many materials can be considered acceptable for simulation and calculation purposes, the work for modeling the real time behavior of phase change materials is still under development. The data given in this article shows the thermal behavior of a flat roof element with a phase change material (PCM) layer. The temperature and energy given to and taken from the building element are reported. In addition the solid-liquid behavior of the PCM is tracked through images. The resulting thermal behavior of the phase change material is discussed and simulated in [1] A. Tokuç, T. Başaran, S.C. Yesügey, An experimental and numerical investigation on the use of phase change materials in building elements: the case of a flat roof in Istanbul, Build. Energy, vol. 102, 2015, pp. 91-104.Article Citation - WoS: 73Measurement of the Polarization of W Bosons With Large Transverse Momenta in W Plus Jets Events at the Lhc(American Physical Society, 2011) Karapınar, GülerA first measurement of the polarization of W bosons with large transverse momenta in pp collisions is presented. The measurement is based on 36 pb(-1) of data recorded at root s = 7 TeV by the CMS detector at the LHC. The left-handed, right-handed, and longitudinal polarization fractions (f(L), f(R), and f(0), respectively) of W bosons with transverse momenta larger than 50 GeV are determined by using decays to both electrons and muons. The muon final state yields the most precise measurement: (f(L) - f(R))(-) = 0.240 +/- 0.036(syst) +/- 0.031(syst) and f(0)(-) = 0.183 +/- 0.087(stat) +/- 0.123(syst) for negatively charged W bosons and (f(L) - f(R))(+) = 0.310 +/- 0.036(syst) +/- 0.017(syst) and f(0)(+) = 0.171 +/- 0.085(syst) +/- 0.099(syst) for positively charged W bosons. This establishes, for the first time, that W bosons produced in pp collisions with large transverse momenta are predominantly left-handed, as expected in the standard model.Article Citation - WoS: 47Search for Heavy Neutrinos and W-R Bosons With Right-Handed Couplings in a Left-Right Symmetric Model in Pp Collisions at Root S=7 Tev(American Physical Society, 2012) Karapınar, GülerResults are presented from a search for heavy, right-handed muon neutrinos, N-mu, and right-handed W-R bosons, which arise in the left-right symmetric extensions of the standard model. The analysis is based on a 5: 0 fb(-1) sample of proton-proton collisions at a center-of-mass energy of 7 TeV, collected by the CMS detector at the Large Hadron Collider. No evidence is observed for an excess of events over the standard model expectation. For models with exact left-right symmetry, heavy right-handed neutrinos are excluded at 95% confidence level for a range of neutrino masses below the WR mass, dependent on the value of M-WR. The excluded region in the two-dimensional (M-WR, MN mu) mass plane extends to M-WR = 2.5TeV. DOI: 10.1103/PhysRevLett.109.261802Article Citation - WoS: 20Measurement of the Azimuthal Anisotropy of Neutral Pions in Pb-Pb Collisions at Root S-Nn=2.76 Tev(American Physical Society, 2013) Karapınar, GülerFirst measurements of the azimuthal anisotropy of neutral pions produced in Pb-Pb collisions at a center-of-mass energy of root S-NN = 2.76 TeV are presented. The amplitudes of the second Fourier component (upsilon(2)) of the pi(0) azimuthal distributions are extracted using an event-plane technique. The values of upsilon(2) are studied as a function of the neutral pion transverse momentum (p(T)) for different classes of collision centrality in the kinematic range 1.6< p(T)<8.0 GeV/c, within the pseudorapidity interval vertical bar eta vertical bar < 0.8. The CMS measurements of upsilon(2)(p(T)) are similar to previously reported pi(0) azimuthal anisotropy results from root S-NN = 200 GeV Au-Au collisions at RHIC, despite a factor of similar to 14 increase in the centerof-mass energy. In the momentum range 2.5<p(T)<5.0 GeV/c, the neutral pion anisotropies are found to be smaller than those observed by CMS for inclusive charged particles. DOI: 10.1103/PhysRevLett.110.042301Article Citation - WoS: 131Evidence for Associated Production of a Single Top Quark and W Boson in Pp Collisions at Root S=7 Tev(American Physical Society, 2013) Karapınar, GülerEvidence is presented for the associated production of a single top quark and W boson in pp collisions at root s = 7 TeV with the CMS experiment at the LHC. The analyzed data correspond to an integrated luminosity of 4.9 fb(-1). The measurement is performed using events with two leptons and a jet originated from a b quark. A multivariate analysis based on kinematic properties is utilized to separate the t (t) over bar background from the signal. The observed signal has a significance of 4.0 sigma and corresponds to a cross section of 16(-4)(+5) pb, in agreement with the standard model expectation of 15.6 +/- 0.4(-1.2)(+1.0) pb. DOI: 10.1103/PhysRevLett.110.022003Article Citation - WoS: 47Search for Pair Production of Third-Generation Leptoquarks and Top Squarks in Pp Collisions at Root S=7 Tev(American Physical Society, 2013) Karapınar, GülerResults are presented from a search for the pair production of third-generation scalar and vector leptoquarks, as well as for top squarks in R-parity-violating supersymmetric models. In either scenario, the new, heavy particle decays into a tau lepton and a b quark. The search is based on a data sample of pp collisions at root s = 7 TeV, which is collected by the CMS detector at the LHC and corresponds to an integrated luminosity of 4.8 fb(-1). The number of observed events is found to be in agreement with the standard model prediction, and exclusion limits on mass parameters are obtained at the 95% confidence level. Vector leptoquarks with masses below 760 GeV are excluded and, if the branching fraction of the scalar leptoquark decay to a tau lepton and a b quark is assumed to be unity, third-generation scalar leptoquarks with masses below 525 GeV are ruled out. Top squarks with masses below 453 GeV are excluded for a typical benchmark scenario, and limits on the coupling between the top squark, tau lepton, and b quark, lambda'(333) are obtained. These results are the most stringent for these scenarios to date. DOI: 10.1103/PhysRevLett.110.081801Article Citation - WoS: 303Study of the Mass and Spin-Parity of the Higgs Boson Candidate Via Its Decays To Z Boson Pairs(American Physical Society, 2013) Karapınar, GülerA study is presented of the mass and spin-parity of the new boson recently observed at the LHC at a mass near 125 GeV. An integrated luminosity of 17: 3 fb(-1), collected by the CMS experiment in proton-proton collisions at center-of-mass energies of 7 and 8 TeV, is used. The measured mass in the ZZ channel, where both Z bosons decay to e or mu pairs, is 126: 2 +/- 0.6(stat) +/- 0. 2(syst) GeV. The angular distributions of the lepton pairs in this channel are sensitive to the spin-parity of the boson. Under the assumption of spin 0, the present data are consistent with the pure scalar hypothesis, while disfavoring the pure pseudoscalar hypothesis. DOI: 10.1103/PhysRevLett.110.081803