PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7645
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Article Tc-99m Erythromycin Lactobionate Inhalation Scintigraphy in Parenchymal Lung Diseases(Elsevier Science inc, 1999) Durak, H; Aktogu, S; Degirmenci, B; Sayit, E; Ertay, T; Dereli, SWe have investigated Technetium 99m erythromycin lactobionate (Tc 99m EL) clearance from the lungs after inhalation, in the presence of an alveolitis. Eighteen patients (6 sarcoidosis, 7 idiopathic fibrosis, and 5 miliary tuberculosis) were imaged after the patients inhaled 1,110 MBq of Tc 99m EL. Clearance half time for the first 45 min, for 24 h, and retention at 24 h correlated with percentage of lymphocytes in bronchoalveolar lavage fluid (BAL) (r =.729, r =.883, and r =.826, respectively). There was a positive correlation between peripheral penetration (PP) and forced expiratory volume in 1 s (FEV1) (r =.806) and forced vital capacity (FVC) (r =.781). Retention was more marked in sarcoidosis compared with tuberculosis (0.025 < p less than or equal to 0.05). Radioaerosol lung imaging may reflect the pulmonary function impairment in parenchymal lung diseases. Retention of Tc 99m EL may be related to number of BAL cells or presence of a lymphocytic alveolitis. Long residency time of Tc 99m EL in the lungs implies that erythromycin can also be administered by inhalation for therapeutic purposes. NUCL MED BIOL 26;6:695-698, 1999. (C) 1999 Elsevier Science Inc. All rights reserved.Article Citation - WoS: 111Stabilization of Magnetic Iron Oxide Nanoparticles in Biological Media by Fetal Bovine Serum (fbs)(American Chemical Society, 2011) Wiogo, Hilda T. R.; Lim, May; Bulmuş, Volga; Yun, Jimmy; Amal, RoseA facile method of stabilizing magnetic iron oxide nanoparticles (MNPs) in biological media (RPMI-1640) via surface modification with fetal bovine scrum (FBS) is presented herein. Dynamic light scattering (DLS) shows that the size of the MNP aggregates can be maintained at 190 +/- 2 nm for up to 16 h in an RPMI 1640 culture medium containing >= 4 vol % FBS. Under transmission electron microscopy (TEM), a layer of protein coating is observed to cover the MNP surface following treatment with FBS. The adsorption of proteins is further confirmed by X-ray photoelectron spectroscopy (XPS). Gel electrophoresis and LC-MS/MS studies reveal that complement factor I-I, antithrombin, complement factor I, alpha-1-antiproteinase, and apolipoprotein E are the proteins most strongly attached to the surface of all MNP. These surface-adsorbed proteins serve as a linker that aids the adsorption of other serum proteins, such as albumin, which otherwise adsorb poorly onto MNPs. The size stability of FBS-treated MNPs in biological media is attributed to the secondary adsorbed proteins, and the size stability in biological media can be maintained only when both the surface-adsorbed proteins and the secondary adsorbed proteins are present on the particle's surface.Article Citation - WoS: 72Search for a Standard-Model Higgs Boson With a Mass in the Range 145 To 1000 Gev at the Lhc(Springer Verlag, 2013) Karapınar, Güler; CMS CollaborationA search for a standard-model-like Higgs boson in the H -> WW and H -> ZZ decay channels is reported, for Higgs boson masses in the range 145 < m(H) < 1000 GeV. The search is based upon proton-proton collision data samples corresponding to an integrated luminosity of up to 5.1 fb(-1) at root s = 7 TeV and up to 5.3 fb(-1) at root s = 8 TeV, recorded by the CMS experiment at the LHC. The combined upper limits at 95 % confidence level on products of the cross section and branching fractions exclude a standard-model-like Higgs boson in the range 145 < m(H) < 710 GeV, thus extending the mass region excluded by CMS from 127-600 GeV up to 710 GeV.Article Citation - WoS: 33Measurement of the Top-Quark Mass in All-Jets T(t)over-Bar Events in Pp Collisions at ?s=7 Tev(Springer Verlag, 2014) Karapınar, Güler; CMS CollaborationThe mass of the top quark is measured using a sample of t (t) over bar candidate events with at least six jets in the final state. The sample is selected from data collected with the CMS detector in pp collisions at root s = 7 TeV in 2011 and corresponds to an integrated luminosity of 3.54 fb(-1). The mass is reconstructed for each event employing a kinematic fit of the jets to a t (t) over bar hypothesis. The top-quark mass is measured to be 173.49 +/- 0.69 ( stat.) +/- 1.21 ( syst.) GeV. A combination with previously published measurements in other decay modes byCMSyields a mass of 173.54 +/- 0.33 (stat.) +/- 0.96 (syst.) GeV.Article Citation - WoS: 162Search for Invisible Decays of Higgs Bosons in the Vector Boson Fusion and Associated Zh Production Modes(Springer Verlag, 2014) Karapınar, Güler; CMS CollaborationA search for invisible decays of Higgs bosons is performed using the vector boson fusion and associated ZH production modes. In the ZH mode, the Z boson is required to decay to a pair of charged leptons or a bb quark pair. The searches use the 8TeV pp collision dataset collected by the CMS detector at the LHC, corresponding to an integrated luminosity of up to 19.7 fb(-1). Certain channels include data from 7TeV collisions corresponding to an integrated luminosity of 4.9 fb(-1).The searches are sensitive to non-standardmodel invisible decays of the recently observed Higgs boson, as well as additional Higgs bosons with similar production modes and large invisible branching fractions. In all channels, the observed data are consistent with the expected standard model backgrounds. Limits are set on the production cross section times invisible branching fraction, as a function of the Higgs boson mass, for the vector boson fusion and ZH production modes. By combining all channels, and assuming standard model Higgs boson cross sections and acceptances, the observed (expected) upper limit on the invisible branching fraction at m(H) = 125GeV is found to be 0.58 (0.44) at 95% confidence level. We interpret this limit in terms of a Higgs-portal model of dark matter interactions.Article Citation - WoS: 230Searches for Electroweak Production of Charginos, Neutralinos, and Sleptons Decaying To Leptons and W, Z, and Higgs Bosons in Pp Collisions at 8 Tev(Springer Verlag, 2014) Karapınar, Güler; CMS CollaborationSearches for the direct electroweak production of supersymmetric charginos, neutralinos, and sleptons in a variety of signatures with leptons and W, Z, and Higgs bosons are presented. Results are based on a sample of proton-proton collision data collected at center-of-mass energy root s = 8 TeV with the CMS detector in 2012, corresponding to an integrated luminosity of 19.5 fb(-1). The observed event rates are in agreement with expectations from the standard model. These results probe charginos and neutralinos with masses up to 720 GeV, and sleptons up to 260 GeV, depending on the model details.Article Citation - WoS: 312Observation of the Diphoton Decay of the Higgs Boson and Measurement of Its Properties(Springer Verlag, 2014) Karapınar, Güler; CMS CollaborationObservation of the diphoton decay mode of the recently discovered Higgs boson and measurement of some of its properties are reported. The analysis uses the entire dataset collected by the CMS experiment in proton-proton collisions during the 2011 and 2012 LHC running periods. The data samples correspond to integrated luminosities of 5.1 fb(-1) at root s = 7 TeV and 19.7 fb(-1) at 8 TeV. A clear signal is observed in the diphoton channel at a mass close to 125 GeV with a local significance of 5.7 sigma, where a significance of 5.2 sigma is expected for the standard model Higgs boson. The mass is measured to be 124.70 +/- 0.34 GeV = 124.70 +/- 0.31 (stat) +/- 0.15 (syst) GeV, and the best-fit signal strength relative to the standard model prediction is 1.14(-0.23)(+0.26) = 1.14 +/- 0.21 (stat) (-0.05)(+0.09) (syst) (+0.13)(-0.09) (theo). Additional measurements include the signal strength modifiers associated with different production mechanisms, and hypothesis tests between spin-0 and spin-2 models.Article Citation - WoS: 38Measurement of Electroweak Production of Two Jets in Association With a Z Boson in Proton-Proton Collisions at ?s=8 Tev(Springer Verlag, 2015) Karapınar, Güler; CMS CollaborationThe purely electroweak (EW) cross section for the production of two jets in association with a Z boson, in proton-proton collisions at root s = 8 TeV, is measured using data recorded by the CMS experiment at the CERN LHC, corresponding to an integrated luminosity of 19.7 fb(-1). The electroweak cross section for the lljj final state (with l = e or mu and j representing the quarks produced in the hard interaction) in the kinematic region defined by M-ll > 50 GeV, M-jj > 120 GeV, transverse momentum p(Tj) > 25 GeV, and pseudorapidity vertical bar eta(j)vertical bar < 5, is found to be sigma(EW) (lljj) = 174 +/- 15 (stat) +/- 40 (syst) fb, in agreement with the standard model prediction. The associated jet activity of the selected events is studied, in particular in a signal-enriched region of phase space, and the measurements are found to be in agreement with QCD predictions.Article Citation - WoS: 66Measurement of the Inclusive 3-Jet Production Differential Cross Section in Proton-Proton Collisions at 7 Tev and Determination of the Strong Coupling Constant in the Tev Range(Springer Verlag, 2015) Karapınar, GülerThis paper presents a measurement of the inclusive 3-jet production differential cross section at a proton-proton centre-of-mass energy of 7 TeV using data corresponding to an integrated luminosity of 5 fb(-1) collected with the CMS detector. The analysis is based on the three jets with the highest transverse momenta. The cross section is measured as a function of the invariant mass of the three jets in a range of 445-3270 GeV and in two bins of the maximum rapidity of the jets up to a value of 2. A comparison between the measurement and the prediction from perturbative QCD at next-to-leading order is performed. Within uncertainties, data and theory are in agreement. The sensitivity of the observable to the strong coupling constant alpha(S) is studied. A fit to all data points with 3-jet masses larger than 664 GeV gives a value of the strong coupling constant of alpha(S)(M-Z) = 0.1171 +/- 0.0013 (exp) (+0.0073)(-0.0047) (theo).Article Citation - WoS: 80Citation - Scopus: 74Measurements of Differential and Double-Differential Drell-Yan Cross Sections in Proton-Proton Collisions at ?s=8 Tev(Springer Verlag, 2015) Karapınar, Güler; CMS CollaborationMeasurements of the differential and double-differential Drell-Yan cross sections in the dielectron and dimuon channels are presented. They are based on proton-proton collision data at root s = 8 TeV recorded with the CMS detector at the LHC and corresponding to an integrated luminosity of 19.7 fb(-1). The measured inclusive cross section in the Z peak region (60-120 GeV), obtained from the combination of the dielectron and dimuon channels, is 1138 +/- 8 (exp) +/- 25 (theo) +/- 30 (lumi) pb, where the statistical uncertainty is negligible. The differential cross section d sigma/dm in the dilepton mass range 15-2000 GeV is measured and corrected to the full phase space. The double-differential cross section d(2)sigma/dm d vertical bar y vertical bar is also measured over the mass range 20 to 1500 GeV and absolute dilepton rapidity from 0 to 2.4. In addition, the ratios of the normalized differential cross sections measured at root s = 7 and 8 TeV are presented. These measurements are compared to the predictions of perturbative QCD at next-to-leading and next-to-next-to-leading (NNLO) orders using various sets of parton distribution functions (PDFs). The results agree with the NNLO theoretical predictions computed with FEWZ 3.1 using the CT10 NNLO and NNPDF2.1 NNLO PDFs. The measured double-differential cross section and ratio of normalized differential cross sections are sufficiently precise to constrain the proton PDFs.