Food Engineering / Gıda Mühendisliği
Permanent URI for this collectionhttps://hdl.handle.net/11147/12
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Conference Object The Importance of Loco-Regional Tumor Burden and Surgery on Survival in Patients With De Novo Stage Iv Breast Cancer; Post-Hoc Analyses of Protocol Mf07-01(American Association for Cancer Research, 2017) Özmen, Vahit; Özbaş, Serdar; Karanlık, Hasan; Müslümanoğlu, Mahmut; İğci, Abdullah; Cantürk, Z.; Sezgin, EfeBackground: The MF07-01 trial is a multicenter phase III randomized controlled trial of treatment naive stage IV BC patients comparing loco-regional surgery (LRS) followed by appropriate systemic therapy (ST) versus ST alone. Aims: To evaluate the importance of loco-regional tumor burden and surgery on overall survival rate in patients with de novo stage IV breast cancer.Book Part Strategies for Controlling Major Enzymatic Reactions in Fresh and Processed Vegetables(Taylor & Francis, 2016) Yemenicioğlu, Ahmet[No abstract available]Article Citation - WoS: 3Citation - Scopus: 3Effect of Different Raw Materials on Aroma Fingerprints of 'boza Using an E-Nose and Sensory Analysis(Wageningen Academic Publishers, 2019) Kemahlıoğlu, Kemal; Kendirci, Perihan; Kadiroğlu, Pınar; Yücel, Ufuk; Korel, FigenBoza is a Turkish traditional beverage produced by fermentation of maize, rice, wheat, millet, cracked wheat, and durum clear flour. The aim of this study was to determine the effect of different raw material combinations on the aroma fingerprints of boza samples using an electronic nose equipped with surface acoustic wave detector in combination with sensory analysis. According to flavour profile analysis of boza samples, significant differences were obtained among the samples. Hierarchical clustering analysis of e-nose and sensory analyses indicated that boza samples were clustered based on their aroma profiles, odour and taste properties revealing the effect of different cereals as raw materials. Rheological analysis showed that all boza samples exhibited pseudoplastic flow behaviour as the apparent viscosity decreased with increasing shear rate. This revealed that differences in raw materials did not change flow behaviour of boza samples. The results indicated that e-nose could be used as a fast and non-destructive method to assess the influence of raw material formulation on aroma profiles of boza samples in correlation with sensory analysis.Article Citation - WoS: 5Citation - Scopus: 5Chemometric Analysis of Chemo-Optical Data for the Assessment of Olive Oil Blended With Hazelnut Oil(Stazione Sperimentale per le Industrie, 2019) Kadiroğlu, Pınar; Korel, Figen; Pardo, MatteoThe main objective of this study was to determine different hazelnut oil concentrations in extra virgin olive oil (EV00) belonging to different geographical regions inside Turkey using the combination of a SAW sensor based electronic nose (e-nose) and a machine vision system (MVS). We leveraged the oil characterisation given by the two easy-to-use and complementary experimental techniques through the adoption of conventional PCA for data exploration and random forests (RF) for supervised learning. The e-nose/MVS combination allows significantly better results both in adulteration detection independently of EVOO's geographical provenance and in EVO0 geographical provenance determination, independently of the adulteration level, with respect to the single characterisation method. RF analysis also produces feature ranking, permitting to shed light on which oils' characteristics influence the learning result. We found that EV00 geographical provenance discrimination is mainly due to yellowness and guaiacol content, while (E)-2-hexenal chiefly determines the prediction of the hazelnut level.Article Citation - WoS: 11Citation - Scopus: 12Characterization of the Self-Assembly and Size Dependent Structural Properties of Dietary Mixed Micelles by Molecular Dynamics Simulations(Elsevier Ltd., 2019) Tuncer, Esra; Bayramoğlu, BesteThe bile salts and phospholipids are secreted by the gallbladder to form dietary mixed micelles in which the solvation of poorly absorbed lipophilic drugs and nutraceuticals take place. A comprehensive understanding of the micellization and structure of the mixed micelles are crucial to design effective delivery systems for such substances. In this study, the evolution of the dietary mixed micelle formation under physiologically relevant concentrations and the dependence of structural properties on micelle size were investigated through coarse grained molecular dynamics simulations. The MARTINI force field was used to model cholate and POPC as the representative bile salt and phospholipid, respectively. The micellization behavior was similar under both fasted and fed state concentrations. Total lipids concentration and the micelle size did not affect the internal structure of the micelles. All the micelles were slightly ellipsoidal in shape independent of their size. The extent of deviation from spherical geometry was found to depend on the micellar POPC/cholate ratio. We also found that the surface and core packing density of the micelles increased with micelle size. The former resulted in more perpendicular alignments of cholates with respect to the surface, while the latter resulted in an improved alignment of POPC tails with the radial direction and more uniform core density.Article Citation - WoS: 19Citation - Scopus: 21Physicochemical and Antimicrobial Properties of Oleoresin Capsicum Nanoemulsions Formulated With Lecithin and Sucrose Monopalmitate(Humana Press, 2019) Akbaş, Elif; Söyler, U. Betül; Öztop, Mecit HalilOleoresin capsicum (OC) is an extract of chili pepper containing the active agent capsaicin. In this study, OC-loaded nanoemulsions were prepared by microfluidization and stabilized with sucrose monopalmitate (SMP) and lecithin. The difference in size and distribution of droplets determined the nanoemulsion behavior mainly due to the interaction of emulsifiers between oil and aqueous phase. The hydrophilic interaction between SMP and aqueous phase and the hydrophobic interaction between lecithin and oil phase were monitored with NMR relaxometry. OC nanoemulsion fabricated with SMP showed the best transparency with smallest droplet size (around 34nm) and stable with glycerol after 28days at ambient storage. Lecithin containing nanoemulsions showed improved bioactivity as showing antioxidant (0.82mg DPPH/L) and antimicrobial (3.40 log for Escherichia coli and 4.37 log for Staphylococcus aureus) activity. Finally, results have important implications to determine the appropriate formulation conditions for OC with food-grade surfactants to be used in pharmaceuticals and food industry.Article Citation - WoS: 82Citation - Scopus: 103A Comparative Study of Mid-Infrared, Uv-Visible and Fluorescence Spectroscopy in Combination With Chemometrics for the Detection of Adulteration of Fresh Olive Oils With Old Olive Oils(Elsevier Ltd., 2019) Uncu, Oğuz; Uncu, Oğuz; Özen, Banu; Özen, Fatma BanuThe work aimed to detect and quantify adulteration of fresh olive oils with old olive oils from the previous harvest year by using different spectroscopic approaches in combination with chemometrics. Adulterated samples prepared in varying concentrations (10.50%(v/v)) were analyzed with fluorescence, Fourier transform-infrared (FT-IR), and ultraviolet-visible (UV-vis) spectroscopic methods. Orthogonal partial least square-discriminant analysis (OPLS-DA) and partial least squares (PLS) regression techniques were used for the differentiation of adulterated oils from the pure oils and prediction of adulteration levels, respectively. After the application of various pre-treatment methods, all of the OPLS-DA classification models generated for every spectroscopic technique successfully differentiated adulterated and non-adulterated oils with over 90% correct classification rate. FT-IR + UV-vis and fluorescence spectral data were also successfully used to predict adulteration levels with high coefficient of determinations for both calibration (0.94 and 0.98) and prediction (0.91 and 0.97) models and low error values for calibration (4.22% and 2.68%), and prediction (5.20% and 2.82%), compared to individual FT-IR and UV-vis spectroscopy were obtained. Therefore, FT-IR + UV-vis and fluorescence spectroscopy as being fast and environmentally friendly tools have great potential for both classification and quantification of adulteration practices involving old olive oil.Book Part Citation - Scopus: 10Electronic Nose Technology in Food Analysis(CRC Press, 2016) Korel, Figen; Balaban, Murat Ömer[No abstract available]