Food Engineering / Gıda Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/12

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  • Article
    Citation - WoS: 10
    Citation - Scopus: 10
    An Efficient Method of Improving Essential Oil Retention and Sustained Release of Chitosan Films: Ultrasound-Assisted Preparation of Chitosan Composites With Surface Active Chickpea Proteins
    (Elsevier, 2024) Barış Kavur, Pelin; Yemenicioğlu, Ahmet
    This work aimed at preparing chitosan (CHI) composites with surface active chickpea protein (CP) showing better eugenol (EUG) retention and sustained release capacity than pristine CHI films. For this purpose, ionic complexation of CHI with CP (CHI:CP ratio = 2:1, w/w) in the presence of EUG at pH 5.0 was achieved using mechanical homogenization alone (HM) or in combination with ultrasonic homogenization (HM-HUS). The HM-HUS treatment provided better solubility of CP (4.4-fold), increased emulsified EUG in film-forming solutions, and denser films than HM treatment. The composite films obtained using HM-HUS (FLMCHI-CP-EUG/HM-HUS) retained 1.2–1.4-fold higher EUG after drying, and showed almost 2-fold slower EUG release in air at room temperature than composite films prepared by HM, and control CHI films prepared by HM (FLMCHI-EUG/HM) or HM-HUS (FLMCHI-EUG/HM-HUS). The FLMCHI-CP-EUG/HM-HUS films also showed better moisture barrier and mechanical properties than other films. The developed films were proved in a challenging coating application with onions. Escherichia coli and Listeria innocua counts of inoculated and FLMCHI-CP-EUG/HM-HUS (average coating thickness = 4.5 ± 1.3 μm) coated onions were significantly lower than those of uncoated (2.8 and 3.8 log) and FLMCHI/HM-HUS (1.4 and 1.3 log) coated onions after 5-days at room temperature. FLMCHI-CP-EUG/HM-HUS coating also reduced percentage of sprouted onions from 30 to 10% during storage. EUG odor of coated onions could not have been detected by 80% of panelists after 4 weeks. Compositing with CP boosts the performance of essential oil loaded CHI films by enabling use of film matrix as an encapsulant. © 2024 Elsevier Ltd
  • Article
    Citation - WoS: 21
    Citation - Scopus: 22
    Characterization and Encapsulation Efficiency of Zein Nanoparticles Loaded With Chestnut Fruit Shell, Cedar and Sweetgum Bark Extracts
    (Elsevier, 2023) Konuk Takma, Dilara; Bozkurt, Semra; Koç, Mehmet; Korel, Figen; Şahin Nadeem, Hilal
    Zein nanoparticles (ZNPs) loaded with bioactive extracts of chestnut (Castanea sativa Mill.) shell, cedar (Cedrus libani) and sweetgum (Liquidambar orientalis) bark wastes were produced using different methods. Nanoprecipitation, high-speed homogenization and ultrasonic homogenization allowed the fabrication of ZNPs with particle sizes smaller than 202.40 nm, 430.25 nm and 325.50 nm, respectively. The smallest nanoparticle size was achieved at 132.81 nm for sweetgum bark extract-loaded ZNPs obtained by the nanoprecipitation method. Encapsulation efficiency (EE) was between 34.03 and 96.83% for all zein nanoparticles fabricated under different mixtures and process conditions. Zein concentration and extract ratio played an essential role in the EE of nanoparticles. The best conditions were determined to obtain the desired properties of ZNPs based on particle size, polydispersity index and EE by using a central composite rotatable design. The nanoprecipitation method was more appropriate for producing chestnut and cedar shell/bark extract-loaded nanoparticles. In contrast, the high-speed homogenization method was suitable for producing sweetgum bark extract-loaded nanoparticles. As a result of the encapsulation of various shell/bark extracts within zein nanoparticles, value-added products were generated from wastes having bioactive compounds. The developed zein nanoparticles for each extract type would offer eco-friendly, simple and safe food processing and packaging systems. © 2023
  • Article
    Citation - WoS: 7
    Citation - Scopus: 9
    A Screen-Printed Electrode Modified With Gold Nanoparticles/ Cellulose Nanocrystals for Electrochemical Detection of 4,4'-methylene Diphenyl Diamine
    (Elsevier, 2023) Büyüktaş, Duygu; Ghaani, Masoud; Rovera, Cesare; Carullo, Daniele; Olsson, Richard T.; Korel, Figen; Farris, Stefano
    Developing simple, cost-effective, easy-to-use, and reliable analytical devices if of utmost importance for the food industry for rapid in-line checks of their products that must comply with the provisions set by the current legislation. The purpose of this study was to develop a new electrochemical sensor for the food packaging sector. More specifically, we propose a screen -printed electrode (SPE) modified with cellulose nanocrystals (CNCs) and gold nanoparticles (AuNPs) for the quantification of 4,4'-methylene diphenyl diamine (MDA), which is one of the most important PAAs that can transfer from food packaging materials into food stuffs. The electrochemical performance of the proposed sensor (AuNPs/CNCs/SPE) in the presence of 4,4'- MDA was evaluated using cyclic voltammetry (CV). The modified AuNPs/CNCs/SPE showed the highest sensitivity for 4,4'-MDA detection, with a peak current of 9.81 mu A compared with 7.08 mu A for the bare SPE. The highest sensitivity for 4,4'-MDA oxidation was observed at pH = 7, whereas the detection limit was found at 57 nM and the current response of 4,4'-MDA rose linearly as its concentration increased from 0.12 mu M to 100 mu M. Experiments using real packaging materials revealed that employing nanoparticles dramatically improved both the sensitivity and the selectivity of the sensor, which can be thus considered as a new analytical tool for quick, simple, and accurate measurement of 4,4 '-MDA during converting operations.
  • Article
    Citation - WoS: 16
    Citation - Scopus: 18
    Microencapsulation of a Potential Probiotic Lactiplantibacillus Pentosus and Its Impregnation Onto Table Olives
    (Elsevier, 2022) Elvan, Menşure; Baysal, Ayşe Handan; Harsa, Hayriye Şebnem
    This study aimed to demonstrate some probiotic properties of Lactiplantibacillus pentosus NRRL B-227 and impregnate the strain onto the table olive surfaces. In this respect, antioxidative ability, antibiotic resistance, and survivability after simulated digestion tests were carried out. Microencapsulation was performed using xylan and whey protein concentrate (WPC) using the water-in-oil emulsion technique to maintain cell viability. A vacuum impregnation process was performed to coat olive surfaces with L. pentosus. This strain demonstrated 71.6% DPPH radical scavenging activity and exhibited paramount resistance to antibiotics. The viable cell count of microencapsulated L. pentosus was found as 8 log CFU/g after 72 weeks of storage. After exposure to the simulated oral phase, 1-log reduction was detected, and gastric phase conditions led to a 3-log reduction of viability of microencapsulated as well as non-microencapsulated cells. The viability of microencapsulated L. pentosus on the surface of olives was also evaluated for one-month, and viable cell count was ≥6 log CFU/g. In the light of these findings, L. pentosus with antibiotic and digestion fluids resistant and antioxidant properties were successfully microencapsulated within xylan-WPC complex. Table olives can be considered as a suitable carrier for beneficial microorganisms that satisfies with the expectations of regulations for functional foods.
  • Book Part
    Citation - Scopus: 8
    Uv Processing and Storage of Liquid and Solid Foods: Quality, Microbial, Enzymatic, Nutritional, Organoleptic, Composition and Properties Effects
    (Elsevier, 2021) Hakgüder Taze, Bengi; Pelvan Akgün, Merve; Yıldız, Semanur; Kaya, Zehra; Ünlütürk, Sevcan
    Non-thermal food processing technologies have been explored extensively in recent years in order to develop food products with extended shelf life as well as preserved nutritional and organoleptic characteristics in accordance with the changing consumer demands (Falguera et al., 2011a; Sanchez-Moreno et al., 2009). Ultraviolet (UV) irradiation is one of the non-thermal processes that can be applied to reduce the microbial load in liquid foods and surfaces, and to sterilize food packages and packaging materials, and environments involved in food processes (Jimenez-Sanchez et al., 2017a; Bintsis et al., 2000). UV light is subdivided into three regions as short-wave UV (UV-C, 200 and 280 nm), medium-wave UV (UV-B, 280 to 315 nm), and long wave UV (UV-A, 315 to 400 nm). The different types of effects on microorganisms can be caused by UV light of different wavelengths. The effectiveness of UV light on microorganisms results primarily from the fact that DNA molecules absorb UV photons between 200 and 300 nm, with peak absorption around 260–265 nm. This causes DNA damage by altering the nucleotide base pairing, thereby creating new linkages between adjacent nucleotides, particularly between pyrimidine bases, on the same DNA strand and ultimately results in cell death (Zimmer and Slawson, 2002). Peak et al. (1984) proposed that the dimer formation is not the only requirement to damage the DNA. Absorption of different wavelength photons by different molecular groups in the long DNA molecule can damage or destroy these bond groups. Thus, different bonds in the DNA can be affected with photons of different energy (Neister, 2014).
  • Article
    Citation - WoS: 7
    Citation - Scopus: 6
    Development of a Nano-Modified Glassy Carbon Electrode for the Determination of 2,6-Diaminotoluene (tda)
    (Elsevier, 2021) Büyüktaş, Duygu; Ghaani, Masoud; Rovera, Cesare; Olsson, Richard T.; Korel, Figen; Farris, Stefano
    The objective of this study was to improve the overall performance of a glassy carbon electrode (GCE) for the detection of 2,6-diaminotoluene (TDA), a possibly carcinogenic primary aromatic amines (PAAs) that poses a serious risk for the consumer' health because they can transfer from multilayer food packages including adhesives based on aromatic polyurethane (PU) systems, to the food. The modification of the electrode surface was made by means of multi-walled carbon nanotubes (MWCNTs) and mesopomus carbon nanoparticles (MCNs). The MWCNTs-MCNs/GCE allowed achieving the best performance in terms of sensitivity, as revealed by cyclic voltammetry - CV, with an oxidation peak of 20.95 mu A over 0.079 mu A of the bare GCE. The pH of the medium influenced the oxidation of 2,6-TDA, with highest sensitivity at pH similar to 7. Amperometry experiments led to an estimated detection limit of 0.129 mu M, and three linear ranges were obtained for 2,6-TDA: 0.53-11.37 mu M, 11.37-229.36 mu M, and 229.36-2326.60 mu M. Chronoamperometry experiments combined with Cottrell's theory allowed estimating a diffusion coefficient of 2,6-TDA of 1.34 x 10(-4) cm(2) s(-1). The number of electrons (n similar to 1) involved in the catalytic oxidation of 2,6-TDA was determined according to the Lavimn's theory. Real sample tests demonstrated that the modification of the sensor using nanoparticls allowed to obtain a highly sensitive and selective sensor, which can possibly used as an alternative analytical device for the rapid, easy, and reliable determination of 2,6-TDA.
  • Conference Object
    Does Locoregional Treatment in De Novo Stage Iv Bone-Only Metastatic Breast Cancer Prolong Survival? an Ongoing Multicenter Registry Study
    (Elsevier, 2019) Soran, Atilla; Işık, Arda; Doğan, Lütfi; Sezgin, Efe; Özbaş, Serdar
    Surgical treatment of primary tumor is a controversial treatment of stage IV de novo metastatic breast cancer (BC). This study aims to present early results of the ongoing reg istry in a cohort of patients.
  • Conference Object
    Citation - WoS: 83
    Citation - Scopus: 87
    Primary Surgery With Systemic Therapy in Patients With De Novo Stage Iv Breast Cancer: 10-Year Follow-Up; Protocol Mf07-01 Randomized Clinical Trial
    (Elsevier, 2021) Soran, Atilla; Özmen, Vahit; Özbaş, Serdar; Karanlık, Hasan; Müslümanoğlu, Mahmut; İğci, Abdullah; Cantürk, Nuh Zafer; Utkan, Zafer; Evrensel, Türkkan; Sezgin, Efe
    Background: The aim of this randomized clinical trial was to evaluate the overall survival (OS) data of patients diagnosed with de novo stage IV breast cancer (BC) who received locoregional treatment (LRT) over a 10-year follow-up. Study Design: The MF07-01 is a 1:1 multicenter, randomized clinical trial comparing the LRT with systemic therapy (ST), where ST was given to all patients either immediately after randomization or after surgical resection of the intact primary tumor. Results: A total of 278 patients were randomized and 265 patients were in the final analysis. At 10-year follow-up, survivals were 19% (95% CI 13%–28%) and 5% (95% CI 2%–12%) in the LRT group and ST group, respectively. Median survival was 46 months for the LRT group and 35 months for the ST group, and hazard of death was 29% lower in the LRT group compared with the ST group (hazard ratio [HR] 0.71; 95% CI 0.59–0.86; p = 0.0003). Conclusions: Patients with a diagnosis of de novo stage IV BC who underwent LRT followed by ST had a 14% higher chance of OS by the end of the 10-year follow-up compared with the patients who received only ST. The longer study follow-up revealed that LRT should be presented to patients when discussing treatment options. © 2021 American College of Surgeons
  • Article
    Citation - WoS: 69
    Citation - Scopus: 89
    Pectinase Enzyme-Complex Production by Aspergillus Spp. in Solid-State Fermentation: a Comparative Study
    (Elsevier, 2012) Heerd, Doreen; Yeğin, Sırma; Tarı, Canan; Fernandez Lahore, Marcelo
    A comparative evaluation of three Aspergillus species according to their pectinase production in solid-state fermentation was performed. Solid-state fermentation offers several potential advantages for enzyme production by fungal strains. Utilization of agricultural by-products as low-cost substrates for microbial enzyme production resulted in an economical and promising process. The pectinolytic enzyme activities of two Aspergillus sojae strains were compared to a known producer, Aspergillus niger IMI 91881, and to A. sojae ATCC 20235, which was re-classified as Aspergillus oryzae. Evaluation of polymethylgalacturonase and polygalacturonase activity was performed as well as exo- vs. endo-enzyme activity in the crude pectinase enzyme-complex of the mentioned strains. Furthermore, a plate diffusion assay was applied to determine the presence and action of proteases in the crude extracts. A. sojae ATCC 20235 with highest polymethylgalacturonase activity and highest polygalacturonase activity both exo- and endo-enzyme activity, is a promising candidate for industrial pectinase production, a group of enzymes with high commercial value, in solid-state fermentation processes. Beside the enzymatic assays a protein profile of each strain is given by SDS-PAGE electrophoresis and in addition species-specific zymograms for pectinolytic enzymes were observed, revealing the differences in protein pattern of the A. sojae strains to the re-classified A. oryzae. (C) 2011 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
  • Article
    Citation - WoS: 3
    Citation - Scopus: 4
    Comparison of Radio-Guided Occult Lesion Localization (roll) and Magnetic Occult Lesion Localization (moll) for Non-Palpable Lesions: a Phantom Model Study
    (Elsevier, 2020) Aydoğan, Tumay; Sezgin, Efe; İlvan, Şennur; Yılmaz, Osman Cem; Aslan, Nesrin; Golshan, Mehra; Aydoğan, Fatih
    We sought to compare radio-guided localization and magnetic tracer localization techniques by using a phantom model for excision of nonpalpable breast lesions. There was no difference between the groups in the duration of operative excision, specimen weight, or specimen volume. Magnetic occult lesion localization can be performed in clinics without the need for a nuclear medicine team and radiation safety procedures. Background: Localization of nonpalpable breast cancers can be achieved with several techniques. We sought to compare radio-guided localization (ROLL) and magnetic tracer localization (MOLL) techniques by using a phantom model we previously developed, which can provide an accurate simulation for excision of nonpalpable breast lesions. Materials and Methods: We designed 20 phantom models (10 MOLL, 10 ROLL group) for localization. A handheld gamma probe for the ROLL group and a manual magnetometer (SentiMag) for the MOLL group were used to test the ability of the modality to detect olives in turkey breasts. The excision time for each procedure, specimen size, and weight of the specimens removed from the turkey breasts were recorded. Results: Both techniques resulted in 100% retrieval of the lesions. There was no difference between the groups in the duration of operative excision, specimen weight, or specimen volume. Conclusion: This experimental trial found similar success rates for ROLL and MOLL in localization of occult lesions using the turkey breast phantom model. MOLL can be performed in clinics without the need for a nuclear medicine team and radiation safety procedures. (C) 2019 Elsevier Inc. All rights reserved.