Food Engineering / Gıda Mühendisliği

Permanent URI for this collectionhttps://hdl.handle.net/11147/12

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  • Article
    Development of Microfibrillated Cellulose-Based Films From Globe Artichokes (cynara Scolymus)
    (Elsevier, 2023) Erguner, Merve (Samli); Harsa, Hayriye Sebnem; Ergüner, Merve
    This research developed biodegradable packaging materials for fresh-cut artichokes using the waste of globe artichokes. The extraction of film-forming materials (cellulose, hemicellulose, lignin, and wax fractions) was done with a mild alkaline extraction method. An environmentally friendly mechanical grinding method (Masuko Supermasscolloider) was chosen to produce cellulose microfibrils having 50-200 mu m length and 10-30 mu m width. The presence of micro fibrillated cellulose in films hindered the heat sealing ability, so using microfibrillated cellulose and Carboxymethyl cellulose together in films (with glycerol, stearic acid, and wax incorporation) exhibited better performance. Micro fibrillated cellulose and Carboxymethyl cellulose-based films have good elasticity (16 % strain), tensile strength (0.85 kg/mm), and seal ability (at 170-220 degrees C). Scanning Electron Microscope analyses showed films with smooth surfaces and dense structures (from the cross-sectional area).
  • Article
    Citation - WoS: 5
    Citation - Scopus: 6
    The Correlation of Magee Equationstm and Oncotype Dx® Recurrence Score From Core Needle Biopsy Tissues in Predicting Response To Neoadjuvant Chemotherapy in Er+ and Her2- Breast Cancer
    (Galenos Publishing House, 2020) Soran,A.; Tane,K.; Sezgin,E.; Bhargava,R.
    Objective: Oncotype DX® recurrence score (RS) can be predicted from Magee EquationsTM (MS) postoperatively. The aim of this study is to investigate correlation of MS with RS from pretreatment core needle biopsy (CNB) tissues, and their clinical usefulness in prediction of response to neoadjuvant chemotherapy (NCT) in estrogen receptor-positive and human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer (BC). Materials and Methods: Pretreatment CNB tissue samples from 60 patients with ER+/HER2- invasive BC were analyzed for MS and RS correlation. MS and RS were categorized as follows: low (<18), intermediate (18–30), and high (≥ 31). Percentage Tumor size Reduction (%TR) was used to assess tumor response to NCT, and substantial %TR was defined as at least 50% reduction (≥50%TR). Correlation between MS and RS, and predictive factors for the ≥50%TR achievement were assessed. Results: MS and RS represented a strong correlation (Spearman's correlation; r=0.58, p<0.0001) as a continuous variable. As a categorical variable, the concordance between MS and RS was 43.3%, and it increased to 80% (r=0.61, p=0.003) with the exclusion of the intermediate risk categories. Although, there was pathologic complete response (pCR), MS showed the highest predictive power for the ≥50% TR achievement, none of the factors were statistically significant (p≥0.07). Conclusion: Our study demonstrated that there was a strong correlation between MS and RS from pretreatment biopsy tissue samples in ER+ and HER2- invasive BC. © 2020 by the Author(s).