Patent Koleksiyonu / Patent Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/10761

Browse

Filters

20141

Settings

Has files: YesPublisher: search.filters.publisher.European Patent Office

Search Results

Now showing 1 - 1 of 1
  • Patent
    Three Dimensional Microfluidic Device That Determines Metastatic Capacity and Homing Choices
    (European Patent Office, 2014)
    The invention provides a device that mimics the in vivo tumor microenvironment comprising different cell types, matrices, biological molecules and chemicals. All steps of metastasis, namely, angiogenesis, matrix invasion, cell migration, intravasation, circulation, extravasation and new tumor formation, in addition to homing choices of cancer cells can simultaneously and jointly be investigated using the said microfluidic device. The design of the device with multiple adjacent channels comprising 3D cell-laden or cell free matrices(24, 25, 26, 27, 28, 29) neighboring a flow channel (30) allows determination of metastatic capacity and homing choices of cancer cells.