Özdemir, Ekrem
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Özdemir, E.
Ozdemir, E.
Ozdemir, Ekrem
Ozdemir, E
Özdemir, E
Ozdemir, E.
Ozdemir, Ekrem
Ozdemir, E
Özdemir, E
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Email Address
ekremozdemir@iyte.edu.tr
Main Affiliation
03.02. Department of Chemical Engineering
Status
Current Staff
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WoS Researcher ID
Sustainable Development Goals
1NO POVERTY
0
Research Products
2ZERO HUNGER
0
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3GOOD HEALTH AND WELL-BEING
4
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4QUALITY EDUCATION
2
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5GENDER EQUALITY
0
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6CLEAN WATER AND SANITATION
1
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7AFFORDABLE AND CLEAN ENERGY
5
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8DECENT WORK AND ECONOMIC GROWTH
0
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9INDUSTRY, INNOVATION AND INFRASTRUCTURE
13
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10REDUCED INEQUALITIES
0
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11SUSTAINABLE CITIES AND COMMUNITIES
0
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12RESPONSIBLE CONSUMPTION AND PRODUCTION
2
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13CLIMATE ACTION
5
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14LIFE BELOW WATER
0
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15LIFE ON LAND
0
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16PEACE, JUSTICE AND STRONG INSTITUTIONS
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17PARTNERSHIPS FOR THE GOALS
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Documents
22
Citations
2043
h-index
14

Documents
20
Citations
1747

Scholarly Output
37
Articles
17
Views / Downloads
41950/15881
Supervised MSc Theses
13
Supervised PhD Theses
2
WoS Citation Count
514
Scopus Citation Count
583
Patents
0
Projects
10
WoS Citations per Publication
13.89
Scopus Citations per Publication
15.76
Open Access Source
26
Supervised Theses
15
| Journal | Count |
|---|---|
| Energy and Fuels | 3 |
| American Chemical Society (ACS) Meeting | 2 |
| Journal of Crystal Growth | 2 |
| Clinical & Experimental Metastasis | 1 |
| Colloids and Surfaces A: Physicochemical and Engineering Aspects | 1 |
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37 results
Scholarly Output Search Results
Now showing 1 - 10 of 37
Conference Object Pen Holder Design for a Handwriting Education Assistance Robot(Springer Science and Business Media B.V., 2025) Güler, O.; Özdemir, Ekrem; Özdemir, E.; Dede, Mehmet İsmet Can; Balkan, M.A.; Öztürk, Ç.; Dede, M.İ.C.The aim of this work is to contribute to quality education by developing a robot system that can assist in handwriting education. The effects of educational robots on learning motivation and performance enhancement have been proven by various studies. In this context, the handwriting assistive robot aims to ease the work of teachers by enabling students to learn how to write more easily and to provide a platform where students can learn on their own. This robot can contribute to the spread of quality education by supporting equal educational opportunities, especially in disadvantaged areas and in cases where the number of teachers is insufficient. The robot supports three different operation modes: Active Mode, Assistive Mode, and Passive Mode. In this study, the pen holder design of this robot is presented. The final design is suitable for both right- and left-handed users, does not require an additional sensor, and the writing ergonomics is increased by keeping the contact point of the pen with the paper at a constant point independent of the holding style. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.Master Thesis Production and Characterization of Heat Insulating Panels(Izmir Institute of Technology, 2016) Yörük, Osman Giray; Özdemir, Ekrem; Özdemir, EkremHollow nano calcite particles were used as a core material in vacuum insulation panels (VIPs) and compared it with the fumed silica generally used in VIPs as the core material. Zinc-Tin-oxide (ZTO), ZnSnOx, was coated on the polyamide/polyethylene (PA/PE) polymeric films and used as the barrier material in VIPs to prohibit moisture and air transport. A fluidized bed filtration system was developed to separate the produced hollow nano particles from its slurry. ZnSnOx coating on the PA/PE polymeric films were optimized with respect to film rotation rate and oxygen content during film coating. Water permeation rate was measured as 8.32 gday-1m-2 for the commercial Aluminum-PET (Al-PET). The water permeation rate was measured as 1.15 gday-1m-2 for the 90 μm of PA/PE films coated with ZTO in 500 rpm of film rotation rate and 30 sccm Ar + 7.5 sccm O2 feed rate. It was shown that the produced ZTO coated PA/PE films had better barrier properties compared to the commercial Al-PET. The thermal conductivity was measured as 8.63 mWm-1K-1 for 3 wt% hollow nano calcite in 87 wt% of fumed silica compared to that of 9.9 mWm-1K-1 for fumed silica only. It was shown that when 3 wt% of hollow nano calcite were mixed with fumed silica as the core material, better thermal conductivity values were obtained.Article Citation - WoS: 21Citation - Scopus: 22Role of Ph on Co2 Sequestration in Coal Seams(Elsevier Ltd., 2016) Özdemir, EkremThe effect of acidic or basic pre-treatment on the adsorption capacity of CO2 on coals was investigated. Argonne Premium Pocahontas No. 3, Upper Freeport, Pittsburgh No. 8, Lewiston-Stockton, Blind Canyon, Illinois No. 6, Wyodak, and Beulah-Zap coals were washed in weak solutions of H2SO4 and NaOH to the pH values of 10, 7, and 2, after an initial washing in acidic water. Attempts to treat the Wyodak and Beulah-Zap coals were unsuccessful because the base treatment after the initial acid treatment resulted in a suspension which could be separated neither via filtration through a 45 μm filter nor centrifugation. Equilibration took several days in some cases, although the as-received coal had been ground to 150 μm. Acid washing preferentially removed Ca (calcite) and Mg. Aluminosilicate clays were not notably removed. Iron was removed in significant amounts only after base treatment, possibly after it was converted to hematite. The adsorption capacity of CO2 on the acid treated coals was higher than both the base treated and untreated coals. The difference in adsorption capacities for acid and base treated coals was related to the pore sizes and mineral matter removal from the coals, where the calculated average pore size was higher for acid treated coals than for the base treated coals. It is concluded that the pH decrease due to CO2 dissolution in cleat water is favored in coal seam sequestration, which resulted in an increase in storage capacity of coals.Conference Object Investigation of Therapeutic Effects of Doxorubicin Loaded Microbubbles in In-Vivo Breast Cancer Model(Springer, 2017) Serinan, Efe Özgür; Barış, Mustafa; Kürkçü, Gülşah; Önercan, Cansu; Çalışır, Meryem; Altun, Zekiye; Aktaş, Safiye; Aydın, Melek; Kılıç Özdemir, Sevgi; Yılmaz, Osman; Özdemir, Ekrem[No abstract available]Conference Object Development of Innovative Multifunctional Nanocarriers for Doxorubicin-Resistant Breast Cancer(Wiley, 2025) Ozsengezer, S. Kum; Altun, Z.; Ozdemir, S. Kilic; Ozdemir, E.Article Citation - WoS: 88Citation - Scopus: 108Biomimetic Co2 Sequestration: 1. Immobilization of Carbonic Anhydrase Within Polyurethane Foam(American Chemical Society, 2009) Özdemir, EkremBovine carbonic anhydrase (CA) was immobilized within polyurethane (PU) foam for biomimetic CO2 sequestration. The catalytic activities for the free and immobilized CA were estimated using paranitrophenyl acetate (p-NPA) as the substrate. Because the p-NPA has limited solubility in the aqueous phase, the activities were estimated in Tris buffer containing 10% acetonitrile. A Lineweaver-Burk relationship was employed to estimate the Michaelis-Menten kinetic parameters for the free and immobilized CA. The kcat, K m, and kcat/Km values for the free CA were found to be 2.02 s-1, 12.2 mM, and 166.4M-1 s-1, respectively. The Km value for the immobilized CA was estimated to be 9.6mMat the same conditions. The immobilized CA was stable and did not lose any activity over seven consecutive washings and activity tests. While the free CA lost its activity in 45 days stored at 4 °C in refrigerator, the immobilized CA maintained 100% of its activity over a 45 day period stored in Tris buffer at ambient conditions. It was concluded that the immobilized CA as a very stable biocatalyst could be employed in biomimetic CO2 sequestration.Article Citation - WoS: 23Citation - Scopus: 31Nano-Caco3 Synthesis by Jet Flow(Elsevier Ltd., 2017) Ülkeryıldız, Eda; Kılıç, Sevgi; Özdemir, EkremA new methodology was introduced to produce hollow nano calcite particles in homogenous size distribution without aggregation. The design consisted of a jet flow system in which the crystallization region was separated from the stabilization region. The newly produced nano CaCO3 particles of about 140 nm were removed from the crystallization region as quickly as possible into the stabilization region before aggregation or crystal growth. In the stages of crystallization, the particles started to dissolve from their edges which opened-up the pores inside the particles. At the late stages of crystallization, the open pores closed. These particles were stable in Ca(OH)2 solution and no aggregation was detected. Different particles with different morphologies can be produced by adjusting the stages in the crystallization.Master Thesis Nano calcite (CaCO3) production in semi-batch bubble reactor(Izmir Institute of Technology, 2013) Ülkeryıldız, Eda; Özdemir, EkremCalcium carbonate (CaCO3) has been widely used as filling material in many industries due to its low cost and enhancement in some of the physical properties of the composite materials. The main purpose of this study was to produce CaCO3 particles by carbonation method in nano size, homogeneous size distribution and different morphologies. A semi-batch bubble reactor was designed in order to introduce carbon dioxide (CO2) into the Ca(OH)2 solution or its slurry with a controlled fashion. Different parameters such as stirring rate, Ca(OH)2 concentration, CO2 flow rate, and pulse CO2 injection were examined. Also, jet flow was applied in the stirred tank reactor to prevent particles from aggregation. Conductivity and pH values of solutions were monitored during crystallization. Zeta potential values and average particle size were measured instantly by dynamic light scattering (DLS). Particles produced were separated by centrifugation, dried at 105 oC in an oven for 1 day, and characterized by the Scanning Electron Microscopy (SEM) for their morphology, and X-Ray diffraction (XRD) for their crystal structures. On the basis of XRD analysis, the main crystal form of precipitated particles was calcite. According to SEM images, elongated chain-like, cubical, and rectangular particles were achieved to be produced with particle size of about 200 nm to 400 nm.Article Lipid Monolayer Composition and Production Efficiency in DSPC/PEG40St Microbubbles for Ultrasound Applications(Elsevier, 2025) Kilic, Sevgi; Ozdemir, EkremLipid-coated microbubbles are widely used as ultrasound contrast agents (UCAs) and are being developed as carriers for drug and gene delivery. These microbubbles typically consist of an inert gas core and a stabilizing monolayer shell of phospholipid and a PEGylated emulsifier. In practice, a 9:1 M ratio of DSPC (a saturated phospholipid) to PEG-40-stearate (PEG40St) is conventionally used, under a long-standing assumption that the final composition of the microbubble shell is identical to the initial mixture composition. In this study, we tested that assumption over a wide range of DSPC/PEG40St ratios. Using sonication-based fabrication, we prepared microbubble suspensions with PEG40St fractions from 10 % up to 90 %. We then quantified the shell composition by proton nuclear magnetic resonance (1H NMR) and measured microbubble yield. Contrary to expectation, the PEG40St content in the bubble shells lower than PEG40St added, indicating selective exclusion or "squeezing out" of PEG40St during formation. Only about 4-6 % of the total lipid mixture ended up in the bubble shells and the rest remained as excess in the sub-phase. Thus, 94-96 % of the costly lipid/emulsifier was wasted in the production process. These results overturn the conventional assumption and highlight a critical inefficiency such that substantial amounts of lipid and PEG40St were lost during production, and the bubble yields were low. The findings have important implications for microbubble manufacturing, suggesting that alternative formulations or other production methods are needed to improve efficiency, and thus reduce costs.Master Thesis Design and Preparation of Alkali Liposomes for Drug Delivery(Izmir Institute of Technology, 2019) Güven, Hatice; Özdemir, Ekrem; Altun, Zekiye SultanCancer is one of the deadliest diseases among other illnesses as an uncontrolled cell division. Liposomal technology has commonly been used in cancer therapy. Chemotherapeutical drugs, genetic materials, different imaging agents can be carried with liposomes. They are preferred by several important characteristics that selective passive targeting of tumors, increased stability and therapeutic index (reducing toxicity) via encapsulation and increased circulation life times with size adjustments. One of the indicator in cell cycle is intracellular pH. The aim of this study is to produce PEGylated alkali liposomes to provide cellular uptake in cancer cells and prevent cell division by changing of intracellular pH. Combination of liposomal technology and alkaline therapy in cancer cells may lead to the development of therapeutic strategies without using any drug to overcome chemoresistance and cell proliferation. For this purpose, alkali liposomes containing sodium carbonate (Na2CO3) solution were prepared and tested their effects on 4T1 breast cancer cell lines in vitro. The cell viabilities were evaluated using trypan blue and WST-1 methods. Pictures were taken for cancer cells to differentiate live and dead cells under different alkali liposome conditions for 5 days. It was found that cell medium containing alkali liposomes up to 3% didn’t affect cell growth. However, cell medium containing alkali liposomes greater than 7% significantly affected the 4T1 breast cancer cell growth and decreased the cell viability to about 40%. It was concluded that PEGylated alkali liposomes were prepared different concentrations to decrease or stop cell division of 4T1 breast cancer cell lines in vitro.
