Protection of Lactobacillus Acidophilus Nrrl-B 4495 Under in Vitro Gastrointestinal Conditions With Whey Protein/Pullulan Microcapsules

dc.contributor.author Çabuk, Burcu
dc.contributor.author Tellioğlu Harsa, Şebnem
dc.coverage.doi 10.1016/j.jbiosc.2015.04.014
dc.date.accessioned 2017-06-02T07:50:47Z
dc.date.available 2017-06-02T07:50:47Z
dc.date.issued 2015
dc.description.abstract In this research, whey protein/pullulan (WP/pullulan) microcapsules were developed in order to assess its protective effect on the viability of Lactobacillus acidophilus NRRL-B 4495 under in vitro gastrointestinal conditions. Results demonstrated that WP/pullulan microencapsulated cells exhibited significantly (p ≤ 0.05) higher resistance to simulated gastric acid and bile salt. Pullulan incorporation into protein wall matrix resulted in improved survival as compared to free cells after 3 h incubation in simulated gastric solution. Moreover WP/pullulan microcapsules were found to release over 70% of encapsulated L. acidophilus NRRL-B 4495 cells within 1 h. The effect of encapsulation during refrigerated storage was also studied. Free bacteria exhibited 3.96 log reduction while, WP/pullulan encapsulated bacteria showed 1.64 log reduction after 4 weeks of storage. en_US
dc.description.sponsorship Izmir Institute of Technology, 2011IYTE12 en_US
dc.identifier.citation Çabuk, B., and Tellioğlu Harsa, Ş. (2015). Protection of Lactobacillus acidophilus NRRL-B 4495 under in vitro gastrointestinal conditions with whey protein/pullulan microcapsules. Journal of Bioscience and Bioengineering, 120(6), 650-656. doi:10.1016/j.jbiosc.2015.04.014 en_US
dc.identifier.doi 10.1016/j.jbiosc.2015.04.014
dc.identifier.doi 10.1016/j.jbiosc.2015.04.014 en_US
dc.identifier.issn 1389-1723
dc.identifier.issn 1347-4421
dc.identifier.scopus 2-s2.0-84946482494
dc.identifier.uri http://doi.org/10.1016/j.jbiosc.2015.04.014
dc.identifier.uri https://hdl.handle.net/11147/5679
dc.language.iso en en_US
dc.publisher Elsevier Ltd. en_US
dc.relation.ispartof Journal of Bioscience and Bioengineering en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Encapsulation en_US
dc.subject Lactobacillus acidophilus en_US
dc.subject Probiotics en_US
dc.subject Pullulan en_US
dc.subject Whey protein en_US
dc.title Protection of Lactobacillus Acidophilus Nrrl-B 4495 Under in Vitro Gastrointestinal Conditions With Whey Protein/Pullulan Microcapsules en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.institutional Çabuk, Burcu
gdc.author.institutional Tellioğlu Harsa, Şebnem
gdc.bip.impulseclass C4
gdc.bip.influenceclass C4
gdc.bip.popularityclass C4
gdc.coar.access open access
gdc.coar.type text::journal::journal article
gdc.collaboration.industrial false
gdc.description.department İzmir Institute of Technology. Food Engineering en_US
gdc.description.endpage 656 en_US
gdc.description.issue 6 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q2
gdc.description.startpage 650 en_US
gdc.description.volume 120 en_US
gdc.description.wosquality Q2
gdc.identifier.openalex W588527957
gdc.identifier.pmid 26100319
gdc.identifier.wos WOS:000366765200008
gdc.index.type WoS
gdc.index.type Scopus
gdc.index.type PubMed
gdc.oaire.accesstype BRONZE
gdc.oaire.diamondjournal false
gdc.oaire.impulse 5.0
gdc.oaire.influence 3.913876E-9
gdc.oaire.isgreen true
gdc.oaire.keywords Time Factors
gdc.oaire.keywords Drug Compounding
gdc.oaire.keywords Drug Storage
gdc.oaire.keywords Probiotics
gdc.oaire.keywords Capsules
gdc.oaire.keywords Pullulan
gdc.oaire.keywords Bile Acids and Salts
gdc.oaire.keywords Cold Temperature
gdc.oaire.keywords Gastric Acid
gdc.oaire.keywords Lactobacillus acidophilus
gdc.oaire.keywords Whey Proteins
gdc.oaire.keywords Drug Stability
gdc.oaire.keywords Whey protein
gdc.oaire.keywords Encapsulation
gdc.oaire.keywords Glucans
gdc.oaire.popularity 2.4553911E-8
gdc.oaire.publicfunded false
gdc.oaire.sciencefields 04 agricultural and veterinary sciences
gdc.oaire.sciencefields 0404 agricultural biotechnology
gdc.openalex.collaboration National
gdc.openalex.fwci 2.60106645
gdc.openalex.normalizedpercentile 0.89
gdc.openalex.toppercent TOP 10%
gdc.opencitations.count 33
gdc.plumx.crossrefcites 29
gdc.plumx.mendeley 74
gdc.plumx.pubmedcites 12
gdc.plumx.scopuscites 41
gdc.scopus.citedcount 41
gdc.wos.citedcount 35
relation.isAuthorOfPublication.latestForDiscovery 8d1003fd-8138-4c80-916f-70eae3e5a2ee
relation.isOrgUnitOfPublication.latestForDiscovery 9af2b05f-28ac-4019-8abe-a4dfe192da5e

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