Hidrofobik İlaç Taşıyıcısı Olarak Akrilik Yıldız Blok Kopolimerler
| dc.contributor.author | Genç, Gözde | |
| dc.contributor.author | Batıgün, Ayşegül | |
| dc.contributor.author | Bayraktar, Oğuz | |
| dc.contributor.author | Altıntaş, Özcan | |
| dc.contributor.author | Tunca, Ümit | |
| dc.contributor.author | Hizal, Gürkan | |
| dc.date.accessioned | 2021-01-24T18:32:06Z | |
| dc.date.available | 2021-01-24T18:32:06Z | |
| dc.date.issued | 2009 | |
| dc.description | 14th National Biomedical Engineering Meeting | en_US |
| dc.description.abstract | Amphiphilic poly(methyl methacrylate)-b-poly(acrylic acid) (PMMA-b-PAA) copolymers with 4 and 6 arms were synthesized by Atomic Transfer Radical Polymerization (ATRP). The polymers were characterized by GPC, H-NMR and FTIR analysis. Polymer samples synthesized at various molecular weights between 18-80 kDa were investigated in terms of maximum loading capacity and critical micelle concentration by fluorescence spectroscopy. 4 arm PMMA-b-PAA (MW 30 kDa) was loaded with hydrophobic model drug indomethacin with an extremely high drug loading efficiency (22.5% drug content). Drug loaded polymer formed a stable and biodegradable complex in aqueous medium. | en_US |
| dc.identifier.isbn | 978-1-4244-3605-7 | |
| dc.identifier.scopus | 2-s2.0-70350212680 | |
| dc.identifier.uri | https://hdl.handle.net/11147/10052 | |
| dc.language.iso | tr | en_US |
| dc.publisher | Institute of Electrical and Electronics Engineers Inc. | en_US |
| dc.relation.ispartof | 14th National Biomedical Engineering Meeting, BIYOMUT 2009 | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Hidrofobik İlaç Taşıyıcısı Olarak Akrilik Yıldız Blok Kopolimerler | en_US |
| dc.title.alternative | Acrylic Star Block Copolymers as Hydrophobic Drug Carriers | en_US |
| dc.type | Conference Object | en_US |
| dspace.entity.type | Publication | |
| gdc.author.institutional | Genç, Gözde | |
| gdc.author.institutional | Batıgün, Ayşegül | |
| gdc.author.institutional | Bayraktar, Oğuz | |
| gdc.coar.access | open access | |
| gdc.coar.type | text::conference output | |
| gdc.description.department | İzmir Institute of Technology. Chemical Engineering | en_US |
| gdc.description.publicationcategory | Konferans Öğesi - Uluslararası - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | N/A | |
| gdc.description.wosquality | N/A | |
| gdc.identifier.wos | WOS:000274345400091 | |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.scopus.citedcount | 0 | |
| gdc.wos.citedcount | 0 | |
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