Optimization of Extraction for Antioxidant and Photoprotective Bioactive Compounds From Ulva Rigida
| dc.contributor.author | Toy, Elif | |
| dc.contributor.author | Bicakci, Beyza Tutku | |
| dc.contributor.author | Erdem, Cansu | |
| dc.contributor.author | Sincar, Bahar | |
| dc.contributor.author | Ozdemir, Feyza | |
| dc.contributor.author | Keskin, Melike | |
| dc.contributor.author | Bayraktar, Oguz | |
| dc.date.accessioned | 2025-09-25T18:56:08Z | |
| dc.date.available | 2025-09-25T18:56:08Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | This study presents the development and optimization of a green extraction bioprocess for Ulva rigida, aiming to efficiently recover bioactive compounds with antioxidant and photoprotective properties using response surface methodology (RSM). A Box-Behnken design evaluated the combined effects of ethanol concentration (0-100 %), solid-to-liquid ratio (20-40 mL g-1), and extraction time (8-24 h) on extraction yield, antioxidant capacity, and sun protection factor (SPF). All variables significantly impacted extract quality, with ethanol concentration being the most influential. Optimal conditions (100 % ethanol, 1:20 ratio, 16 h) yielded an extract with SPF 11.61 and antioxidant activity of 16.91 mg Trolox/g. Preparative thin-layer chromatography (TLC) of the optimized extract produced three bioactive fractions exhibiting up to 2.3-fold higher SPF and 5-fold greater antioxidant activity. Liquid chromatography-mass spectrometry (LC-MS) analysis confirmed selective enrichment of carotenoids and polyphenols. These findings demonstrate the value of statistically optimized, bioactivity-guided extraction in enhancing Ulva-derived ingredients for cosmeceutical use. | en_US |
| dc.description.sponsorship | Turkish Scientific and Technological Research Institution [223 M357] | en_US |
| dc.description.sponsorship | We acknowledge the support provided by the Turkish Scientific and Technological Research Institution (Grant number: 223 M357) for funding this research, which was performed under WG 4 (Bioactive chemicals and Ulvaassociated microorganisms) within the scope of Cost Action CA20106-Tomorrow's 'Wheat of The Sea': Ulva, A Model for An Innovative Mariculture (SEAWHEAT). | en_US |
| dc.identifier.doi | 10.1016/j.biteb.2025.102253 | |
| dc.identifier.issn | 2589-014X | |
| dc.identifier.scopus | 2-s2.0-105013275210 | |
| dc.identifier.uri | https://doi.org/10.1016/j.biteb.2025.102253 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.relation.ispartof | Bioresource Technology Reports | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Marine Bioactives | en_US |
| dc.subject | Ulva Rigida | en_US |
| dc.subject | Sun Protection Factor | en_US |
| dc.subject | Green Extraction | en_US |
| dc.subject | Cosmeceuticals | en_US |
| dc.title | Optimization of Extraction for Antioxidant and Photoprotective Bioactive Compounds From Ulva Rigida | |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.institutional | Bayraktar, Oğuz | |
| gdc.author.wosid | Turan, Nurdan/Acf-8055-2022 | |
| gdc.author.wosid | Yalçın, Dilek/C-9020-2019 | |
| gdc.author.wosid | Baldelli, Alberto/Aaw-5914-2021 | |
| gdc.coar.type | text::journal::journal article | |
| gdc.collaboration.industrial | false | |
| gdc.description.department | İzmir Institute of Technology | en_US |
| gdc.description.departmenttemp | [Toy, Elif; Bicakci, Beyza Tutku; Erdem, Cansu; Sincar, Bahar; Ozdemir, Feyza; Keskin, Melike; Bayraktar, Oguz] Ege Univ, Dept Bioengn, Izmir, Turkiye; [Yalcin, Dilek] Izmir Inst Technol, Dept Bioengn, Izmir, Turkiye; [Turan, Gamze] Ege Univ, Fisheries Fac, Aquaculture Dept, TR-35100 Izmir, Turkiye; [Baldelli, Alberto] Univ Queensland, Fac Agr & Food Sustainabil, Brisbane, Australia; [Baldelli, Alberto] Univ Queensland, Queensland Alliance Agr & Food Innovat, Brisbane, Australia | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q2 | |
| gdc.description.volume | 31 | en_US |
| gdc.description.woscitationindex | Emerging Sources Citation Index | |
| gdc.description.wosquality | Q1 | |
| gdc.identifier.openalex | W4413146672 | |
| gdc.identifier.wos | WOS:001579260600001 | |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.openalex.fwci | 0.0 | |
| gdc.openalex.normalizedpercentile | 0.24 | |
| gdc.openalex.toppercent | TOP 10% | |
| gdc.opencitations.count | 0 | |
| gdc.plumx.mendeley | 8 | |
| gdc.plumx.scopuscites | 0 | |
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