Intracytoplasmic Re-Localization of Mirisc Complexes
| dc.contributor.author | Akgül, Bünyamin | |
| dc.contributor.author | Erdoğan, İpek | |
| dc.coverage.doi | 10.3389/fgene.2018.00403 | |
| dc.date.accessioned | 2020-07-25T22:12:45Z | |
| dc.date.available | 2020-07-25T22:12:45Z | |
| dc.date.issued | 2018 | |
| dc.description | PubMed: 30298086 | en_US |
| dc.description.abstract | MicroRNAs (miRNAs) are a conserved class of non-coding RNAs of 22 nucleotides that post-transcriptionally regulate gene expression through translational repression and/or mRNA degradation. A great progress has been made regarding miRNA biogenesis and miRNA-mediated gene regulation. Additionally, an ample amount of information exists with respect to the regulation of miRNAs. However, the cytoplasmic localization of miRNAs and its effect on gene regulatory output is still in progress. We provide a current review of the cytoplasmic miRNA localization in metazoans. We then discuss the dynamic changes in the intracytoplasmic localization of miRNAs as a means to regulate their silencing activity. We then conclude our discussion with the potential molecules that could modulate miRNA localization. | en_US |
| dc.identifier.doi | 10.3389/fgene.2018.00403 | en_US |
| dc.identifier.doi | 10.3389/fgene.2018.00403 | |
| dc.identifier.issn | 1664-8021 | |
| dc.identifier.scopus | 2-s2.0-85055214296 | |
| dc.identifier.uri | https://doi.org/10.3389/fgene.2018.00403 | |
| dc.identifier.uri | https://hdl.handle.net/11147/9514 | |
| dc.language.iso | en | en_US |
| dc.publisher | Frontiers Media S.A. | en_US |
| dc.relation.ispartof | Frontiers in Genetics | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | MicroRNAs | en_US |
| dc.subject | Localization | en_US |
| dc.subject | Polysome | en_US |
| dc.subject | mRNP | en_US |
| dc.subject | Translational repression | en_US |
| dc.title | Intracytoplasmic Re-Localization of Mirisc Complexes | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
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| gdc.author.id | 0000-0001-6415-7654 | en_US |
| gdc.author.id | 0000-0001-9877-9689 | en_US |
| gdc.author.institutional | Akgül, Bünyamin | |
| gdc.author.institutional | Erdoğan, İpek | |
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| gdc.coar.access | open access | |
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| gdc.description.department | İzmir Institute of Technology. Molecular Biology and Genetics | en_US |
| gdc.description.publicationcategory | Diğer | en_US |
| gdc.description.scopusquality | Q2 | |
| gdc.description.volume | 9 | en_US |
| gdc.description.wosquality | Q2 | |
| gdc.identifier.openalex | W2890043581 | |
| gdc.identifier.pmid | 30298086 | |
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| gdc.oaire.keywords | microRNA | |
| gdc.oaire.keywords | Polysome | |
| gdc.oaire.keywords | MicroRNA | |
| gdc.oaire.keywords | QH426-470 | |
| gdc.oaire.keywords | Translational repression | |
| gdc.oaire.keywords | localization | |
| gdc.oaire.keywords | mRNP | |
| gdc.oaire.keywords | Localization | |
| gdc.oaire.keywords | Genetics | |
| gdc.oaire.keywords | polysome | |
| gdc.oaire.keywords | translational repression | |
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| gdc.oaire.sciencefields | 0301 basic medicine | |
| gdc.oaire.sciencefields | 0303 health sciences | |
| gdc.oaire.sciencefields | 03 medical and health sciences | |
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