Computational Approaches for Antibody-Based Drug Design
| dc.contributor.author | Gunes, S. | |
| dc.contributor.author | Arkca, I. | |
| dc.contributor.author | Atik, S.B. | |
| dc.contributor.author | Ulucan-Karnak, F. | |
| dc.contributor.author | Sezgin, H.T. | |
| dc.contributor.author | Uyar, A. | |
| dc.date.accessioned | 2025-02-05T09:52:47Z | |
| dc.date.available | 2025-02-05T09:52:47Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | This chapter includes various aspects of antibodies with a major emphasis on computational tools in antibody design. In this scope, current antibody databases, computational tools, and approaches for modelling antibodies and nanobodies, the structure, and interface prediction are analyzed. On the other hand, various antibody design techniques such as grafting, the significance of antibody-drug conjugates, and how computational methods contribute to the development of therapeutic antibodies are discussed with relevant strategies in the literature. Lastly, the production cost and the rising market value of antibodies are emphasized. © IOP Publishing Ltd 2023. All rights reserved. | en_US |
| dc.identifier.doi | 10.1088/978-0-7503-5613-8ch11 | |
| dc.identifier.isbn | 9780750356152 | |
| dc.identifier.isbn | 9780750356114 | |
| dc.identifier.scopus | 2-s2.0-85213174508 | |
| dc.identifier.uri | https://doi.org/10.1088/978-0-7503-5613-8ch11 | |
| dc.identifier.uri | https://hdl.handle.net/11147/15319 | |
| dc.language.iso | en | en_US |
| dc.publisher | Institute of Physics Publishing | en_US |
| dc.relation.ispartof | Advances in Drug Delivery Systems for Healthcare: From concept to clinic | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | [No Keyword Available] | en_US |
| dc.title | Computational Approaches for Antibody-Based Drug Design | en_US |
| dc.type | Book Part | en_US |
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| gdc.description.department | İzmir Institute of Technology | en_US |
| gdc.description.departmenttemp | Gunes S., Polymer Science and Engineering Master's Program, Izmir Institute of Technology, Izmir, 35430, Turkey; Arkca I., Department of Bioengineering, Izmir Institute of Technology, Izmir, 35430, Turkey; Atik S.B., Department of Bioengineering, Izmir Institute of Technology, Izmir, 35430, Turkey; Ulucan-Karnak F., Department of Medical Biochemistry, Faculty of Medicine, Ege University, Izmir, 35100, Turkey, Institute of Health Sciences, Medical Biochemistry Department, Ege University, Izmir, 35040, Turkey; Sezgin H.T., Department of Bioengineering, Izmir Institute of Technology, Izmir, 35430, Turkey; Uyar A., Department of Bioengineering, Izmir Institute of Technology, Izmir, 35430, Turkey, Computational Science and Engineering Graduate Program, Izmir Institute of Technology, Izmir, 35430, Turkey | en_US |
| gdc.description.publicationcategory | Kitap Bölümü - Uluslararası | en_US |
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