Neo-Clerodanes From Teucrium Divaricatum Subsp. Divaricatum and Their Biological Activity Assessment
| dc.contributor.author | Aydoğan, Fadime | |
| dc.contributor.author | Ali, Zülfiqar | |
| dc.contributor.author | Zülfiqar, Fazila | |
| dc.contributor.author | Karaalp, Canan | |
| dc.contributor.author | Khan, Ikhlas A. | |
| dc.contributor.author | Bedir, Erdal | |
| dc.date.accessioned | 2023-03-07T06:12:35Z | |
| dc.date.available | 2023-03-07T06:12:35Z | |
| dc.date.issued | 2023 | |
| dc.description.abstract | Fifteen neo-clerodane diterpenoids (1–15), including two undescribed glycosides, teudivaricosides A (1) and B (2), together with a known iridoid glycoside (16) and a phenylpropanoid glycoside (17) from the whole plant of Teucrium divaricatum subsp. divaricatum were isolated. Their structures were determined by spectral data analysis including 1D and 2D NMR and HRESIMS. Neo-clerodane diterpenoids were evaluated for their anti-inflammatory, and antimicrobial activities. None of them showed significant antimicrobial activity against various bacterial and fungal strains (up to 20 µg/mL). All tested compounds were inactive up to the highest tested concentration of 50 µM on iNOS inhibitory activity. | en_US |
| dc.identifier.doi | 10.1016/j.phytol.2023.01.010 | |
| dc.identifier.issn | 1874-3900 | en_US |
| dc.identifier.scopus | 2-s2.0-85146858756 | |
| dc.identifier.uri | https://doi.org/10.1016/j.phytol.2023.01.010 | |
| dc.identifier.uri | https://hdl.handle.net/11147/13201 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier | en_US |
| dc.relation.ispartof | Phytochemistry Letters | en_US |
| dc.rights | info:eu-repo/semantics/embargoedAccess | en_US |
| dc.subject | Antimicrobial | en_US |
| dc.subject | iNOS | en_US |
| dc.subject | Lamiaceae | en_US |
| dc.title | Neo-Clerodanes From Teucrium Divaricatum Subsp. Divaricatum and Their Biological Activity Assessment | en_US |
| dc.type | Article | en_US |
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| gdc.author.id | 0000-0003-1262-063X | |
| gdc.author.institutional | Bedir, Erdal | |
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| gdc.contributor.affiliation | Dicle Üniversitesi | en_US |
| gdc.contributor.affiliation | University of Mississippi | en_US |
| gdc.contributor.affiliation | University of Mississippi | en_US |
| gdc.contributor.affiliation | Ege Üniversitesi | en_US |
| gdc.contributor.affiliation | University of Mississippi | en_US |
| gdc.contributor.affiliation | 01. Izmir Institute of Technology | en_US |
| gdc.description.department | İzmir Institute of Technology. Bioengineering | en_US |
| gdc.description.endpage | 49 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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| gdc.description.startpage | 45 | en_US |
| gdc.description.volume | 54 | en_US |
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| gdc.oaire.keywords | Phytochemistry | |
| gdc.oaire.keywords | divaricatum | |
| gdc.oaire.keywords | Lamiaceae | |
| gdc.oaire.keywords | Glucoside | |
| gdc.oaire.keywords | Furanoid Diterpenes | |
| gdc.oaire.keywords | C-12 | |
| gdc.oaire.keywords | Teucrium divaricatum subsp | |
| gdc.oaire.keywords | Lamiaceae neo-clerodane | |
| gdc.oaire.keywords | iNOS | |
| gdc.oaire.keywords | Neoclerodane Diterpenoids | |
| gdc.oaire.keywords | Teucrium divaricatum subsp. | |
| gdc.oaire.keywords | Divaricatum | |
| gdc.oaire.keywords | Chamaedrys | |
| gdc.oaire.keywords | Antimicrobial | |
| gdc.oaire.keywords | neo-clerodane | |
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