Characterization of a Cdna From Beta Maritima That Confers Nickel Tolerance in Yeast
| dc.contributor.author | Bozdağ, Gönensin Ozan | |
| dc.contributor.author | Kaya, Alaattin | |
| dc.contributor.author | Koç, Ahmet | |
| dc.contributor.author | Noll, Gundula A. | |
| dc.contributor.author | Prüfer, Dirk | |
| dc.contributor.author | Karakaya, Hüseyin Çağlar | |
| dc.coverage.doi | 10.1016/j.gene.2014.01.052 | |
| dc.date.accessioned | 2017-05-17T06:52:41Z | |
| dc.date.available | 2017-05-17T06:52:41Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | Nickel is an essential micronutrient due to its involvement in many enzymatic reactions as a cofactor. However, excess of this element is toxic to biological systems. Here, we constructed a cDNA library from Beta maritima and screened it in the yeast system to identify genes that confer resistance to toxic levels of nickel. A cDNA clone (NIC6), which encodes for a putative membrane protein with unknown function, was found to help yeast cells to tolerate toxic levels of nickel. A GFP fused form of Nic6 protein was localized to multivesicular structures in tobacco epidermal cells. Thus, our results suggest a possible role of Nic6 in nickel and intracellular ion homeostasis. | en_US |
| dc.description.sponsorship | IYTE-BAP; DPT | en_US |
| dc.identifier.citation | Bozdağ, G.O., Kaya, A., Koç, A., Noll, G.A., Prüfer, D., and Karakaya, H.Ç. (2014). Characterization of a cDNA from Beta maritima that confers nickel tolerance in yeast. Gene, 538(2), 251-257. doi:10.1016/j.gene.2014.01.052 | en_US |
| dc.identifier.doi | 10.1016/j.gene.2014.01.052 | en_US |
| dc.identifier.doi | 10.1016/j.gene.2014.01.052 | |
| dc.identifier.issn | 0378-1119 | |
| dc.identifier.scopus | 2-s2.0-84893902129 | |
| dc.identifier.uri | https://doi.org/10.1016/j.gene.2014.01.052 | |
| dc.identifier.uri | https://hdl.handle.net/11147/5530 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier Ltd. | en_US |
| dc.relation.ispartof | Gene | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Beta maritima | en_US |
| dc.subject | Heavy metal toxicity | en_US |
| dc.subject | Ion homeostasis | en_US |
| dc.subject | Nickel | en_US |
| dc.subject | Transporter protein | en_US |
| dc.subject | Yeast | en_US |
| dc.title | Characterization of a Cdna From Beta Maritima That Confers Nickel Tolerance in Yeast | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.institutional | Bozdağ, Gönensin Ozan | |
| gdc.author.institutional | Kaya, Alaattin | |
| gdc.author.institutional | Koç, Ahmet | |
| gdc.author.institutional | Karakaya, Hüseyin Çağlar | |
| gdc.author.yokid | 24898 | |
| gdc.bip.impulseclass | C5 | |
| gdc.bip.influenceclass | C5 | |
| gdc.bip.popularityclass | C5 | |
| gdc.coar.access | open access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.collaboration.industrial | false | |
| gdc.description.department | İzmir Institute of Technology. Molecular Biology and Genetics | en_US |
| gdc.description.endpage | 257 | en_US |
| gdc.description.issue | 2 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q2 | |
| gdc.description.startpage | 251 | en_US |
| gdc.description.volume | 538 | en_US |
| gdc.description.wosquality | Q3 | |
| gdc.identifier.openalex | W2070429406 | |
| gdc.identifier.pmid | 24487090 | |
| gdc.identifier.wos | WOS:000333789000006 | |
| gdc.index.type | WoS | |
| gdc.index.type | Scopus | |
| gdc.index.type | PubMed | |
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| gdc.oaire.influence | 2.7763196E-9 | |
| gdc.oaire.isgreen | true | |
| gdc.oaire.keywords | Nicotiana | |
| gdc.oaire.keywords | Heavy metal toxicity | |
| gdc.oaire.keywords | DNA, Complementary | |
| gdc.oaire.keywords | Base Sequence | |
| gdc.oaire.keywords | DNA, Plant | |
| gdc.oaire.keywords | Sequence Homology, Amino Acid | |
| gdc.oaire.keywords | Ion homeostasis | |
| gdc.oaire.keywords | Recombinant Fusion Proteins | |
| gdc.oaire.keywords | Molecular Sequence Data | |
| gdc.oaire.keywords | Saccharomyces cerevisiae | |
| gdc.oaire.keywords | Transporter protein | |
| gdc.oaire.keywords | Genes, Plant | |
| gdc.oaire.keywords | Plants, Genetically Modified | |
| gdc.oaire.keywords | Yeast | |
| gdc.oaire.keywords | Nickel | |
| gdc.oaire.keywords | Inactivation, Metabolic | |
| gdc.oaire.keywords | Beta maritima | |
| gdc.oaire.keywords | Amino Acid Sequence | |
| gdc.oaire.keywords | Beta vulgaris | |
| gdc.oaire.keywords | Cloning, Molecular | |
| gdc.oaire.keywords | Gene Library | |
| gdc.oaire.keywords | Plant Proteins | |
| gdc.oaire.popularity | 2.745335E-9 | |
| gdc.oaire.publicfunded | false | |
| gdc.oaire.sciencefields | 0301 basic medicine | |
| gdc.oaire.sciencefields | 0303 health sciences | |
| gdc.oaire.sciencefields | 03 medical and health sciences | |
| gdc.openalex.collaboration | International | |
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| gdc.scopus.citedcount | 4 | |
| gdc.wos.citedcount | 5 | |
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