Role of Autophagy in the Progression and Suppression of Leukemias

dc.contributor.author Ekiz, Hüseyin Atakan
dc.contributor.author Can, Geylani
dc.contributor.author Baran, Yusuf
dc.coverage.doi 10.1016/j.critrevonc.2011.03.009
dc.date.accessioned 2017-02-10T07:20:40Z
dc.date.available 2017-02-10T07:20:40Z
dc.date.issued 2012
dc.description.abstract Autophagy is a physiological process in which cellular components are degraded by the lysosomal machinery. Thereby, organelles are recycled and monomers are produced in order to maintain energy production. Current studies indicate autophagy might suppress or augment survival of cancer cells. Therefore, by elucidating the role of autophagy in cancer pathogenesis, novel therapeutic intervention points may be revealed. Leukemia therapy has advanced in recent years; but a definitive cure is still lacking. Since autophagy often is deregulated in this particular type of cancer, it is clear that future findings will have clinical implications. This review will discuss the current knowledge of autophagy in blood cancers. © 2011 Elsevier Ireland Ltd. en_US
dc.identifier.citation Ekiz, H. A., Can, G., and Baran, Y. (2012). Role of autophagy in the progression and suppression of leukemias. Critical Reviews in Oncology/Hematology, 81(3), 275-285. doi:10.1016/j.critrevonc.2011.03.009 en_US
dc.identifier.doi 10.1016/j.critrevonc.2011.03.009 en_US
dc.identifier.doi 10.1016/j.critrevonc.2011.03.009
dc.identifier.issn 1040-8428
dc.identifier.scopus 2-s2.0-84856974622
dc.identifier.uri http://doi.org/10.1016/j.critrevonc.2011.03.009
dc.identifier.uri https://hdl.handle.net/11147/4827
dc.language.iso en en_US
dc.publisher Elsevier Ltd. en_US
dc.relation.ispartof Critical Reviews in Oncology/Hematology en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Leukemia en_US
dc.subject Chemotherapeutic resistance en_US
dc.subject Cell death en_US
dc.subject Autophagy en_US
dc.title Role of Autophagy in the Progression and Suppression of Leukemias en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.id 0000-0001-7718-6841
gdc.author.id 0000-0001-7718-6841 en_US
gdc.author.institutional Ekiz, Hüseyin Atakan
gdc.author.institutional Can, Geylani
gdc.author.institutional Baran, Yusuf
gdc.bip.impulseclass C4
gdc.bip.influenceclass C5
gdc.bip.popularityclass C5
gdc.coar.access open access
gdc.coar.type text::journal::journal article
gdc.collaboration.industrial false
gdc.description.department İzmir Institute of Technology. Molecular Biology and Genetics en_US
gdc.description.endpage 285 en_US
gdc.description.issue 3 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q1
gdc.description.startpage 275 en_US
gdc.description.volume 81 en_US
gdc.description.wosquality Q1
gdc.identifier.openalex W2058677968
gdc.identifier.pmid 21612942
gdc.identifier.wos WOS:000301561200005
gdc.index.type WoS
gdc.index.type Scopus
gdc.index.type PubMed
gdc.oaire.accesstype BRONZE
gdc.oaire.diamondjournal false
gdc.oaire.impulse 8.0
gdc.oaire.influence 3.3290584E-9
gdc.oaire.isgreen false
gdc.oaire.keywords Leukemia
gdc.oaire.keywords Cell Survival
gdc.oaire.keywords Autophagy
gdc.oaire.keywords Animals
gdc.oaire.keywords Humans
gdc.oaire.keywords Energy Metabolism
gdc.oaire.keywords Lysosomes
gdc.oaire.popularity 3.6076582E-9
gdc.oaire.publicfunded false
gdc.oaire.sciencefields 0301 basic medicine
gdc.oaire.sciencefields 0303 health sciences
gdc.oaire.sciencefields 03 medical and health sciences
gdc.openalex.collaboration National
gdc.openalex.fwci 0.90193938
gdc.openalex.normalizedpercentile 0.73
gdc.opencitations.count 21
gdc.plumx.crossrefcites 17
gdc.plumx.mendeley 41
gdc.plumx.pubmedcites 10
gdc.plumx.scopuscites 25
gdc.scopus.citedcount 25
gdc.wos.citedcount 23
relation.isAuthorOfPublication.latestForDiscovery 7bb863bb-9384-4a07-9fbb-b9c1ab7634a3
relation.isOrgUnitOfPublication.latestForDiscovery 9af2b05f-28ac-4013-8abe-a4dfe192da5e

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