Peptıde Targeted Core Cross-lınked Mıcelles For Dox Delıvery To Her2 Expressıng Cancer Cells
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Abstract
In this study, we prepared a novel targeted and extra stable micellar nanocarrier that can facilitate intracellular drug release. First, ((N-3-sulfopropyl-N, N-dimethylammonium)ethyl methacrylate was synthesized by RAFT polymerization, and it was followed by copolymerization of macroCTA with AEM in the presence of an aciddegradable cross-linker. Then, a peptide estimated by phage display for HER-2 recognition was incorporated into these core cross-linked micelles with carbodiimide reaction.
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Fields of Science
0301 basic medicine, 0303 health sciences, 03 medical and health sciences
Citation
WoS Q
Q3
Scopus Q
Q2
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N/A
Source
Tissue Engineering Part A
Volume
28
Issue
S1
Start Page
S
End Page
1
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Mendeley Readers : 22
