Comparative Mapping

Abstract

In the mid 1980s, restriction fragment length polymorphism (RFLP) analysis was first applied to plants for the purposes of creating genetic linkage maps. Using the maps developed for major crop species, the genes controlling qualitative and quantitative traits could be detected and then selected for (via closely linked molecular markers) in breeding programs. Advances in DNA marker technology not only allowed the rapid generation of high-resolution plant genetic maps, but also facilitated detailed comparisons among species. When complementary molecular markers are mapped across related species, it is then possible to align the chromosomes of those species to create comparative linkage maps. In this way, genomic similarities between species are revealed so that genetic information about one species may be extended to others and evolutionary inferences drawn. © 2008, CRC Press. All rights reserved.