Biotransformation of Cyclocanthogenol by the Endophytic Fungus Alternaria Eureka 1e1bl1
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BRONZE
Green Open Access
Yes
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1
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2
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No
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Abstract
The microbial transformation of cyclocanthogenol (CCG), Astragalus sp. originated sapogenin, by the endophytic fungus Alternaria eureka 1E1BL1 isolated from Astragalus angustifolius was investigated. Hydroxylation, oxidation, epoxidation, O-methylation, ring-expansion and methyl migration reactions were observed on the triterpenoid skeleton. As a result, eight metabolites were isolated and the structures of the previously undescribed compounds were established by 1-D, 2-D NMR and HR-MS analyses.
Description
Keywords
Alternaria eureka, Astragalus, Biotransformation, Cycloartanes, Cyclocanthogenol, Endophytic fungus, Fabaceae, Sapogenins, Astragalus, Molecular Conformation, Alternaria, Fabaceae, Stereoisomerism, Cycloartanes, Alternaria eureka, Cyclocanthogenol, Biotransformation, Endophytic fungus
Fields of Science
0301 basic medicine, 0303 health sciences, 03 medical and health sciences
Citation
Ekiz, G., Duman, S., and Bedir, E. (2018). Biotransformation of cyclocanthogenol by the endophytic fungus Alternaria eureka 1E1BL1. Phytochemistry, 154, 91-98. doi:10.1016/j.phytochem.2018.04.006
WoS Q
Scopus Q
OpenCitations Citation Count
26
Source
Volume
151
Issue
Start Page
91
End Page
98
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Scopus : 30
PubMed : 7
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