Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
83 results
Search Results
Article Citation - WoS: 2Citation - Scopus: 2A Comprehensive Study on the Effectiveness of the Stress and Damage Model Parameters in Predicting the Compression Fracture Behavior of Selective Laser Melted AlSi10Mg BCC Lattices(Elsevier B.V., 2025) Guden, Mustafa; Erten, Hacer Irem; Gorguluarslan, Recep M.; Gulletutan, Umut Can; Dagkolu, Akin; Gokdag, Istemihan; Namazov, SubhanThe Johnson and Cook (JC) stress and damage model parameters determined from the machined bulk cylindrical specimens and as-built struts through tension and compression tests were used to model quasi-static compression behavior of selective laser melt-fabricated AlSi10Mg alloy lattices. The lattices had the same cell size (10 mm) and strut diameter (1 mm), but different number of cells (2 x 2 x 2, 10 x 10 x 2 and 5 x 5 x 5) and geometries (sandwich and cubic). Four different sets of JC damage model parameters (brittle and ductile notch-insensitive and compression and tension notch-sensitive) were further implemented in the lattice compression numerical models. The brittle damage model parameters and smaller mesh sizes resulted in cracking the face-sheet corner strut nodes before the occurrence of a bending-dominated initial peak stress. The notch-sensitive damage model parameters exhibited no bent-strut fracture in the middle layers of the lattices and increased the crack initiation strains as compared with the notch-insensitive damage model parameters. Despite significant variations in the initial peak stresses of the tested 2 x 2 x 2 and 10 x 10 x 2 lattices, the implication of the strut micro-tension stress model together with the compression notch-sensitive damage model parameters using 0.25 mm mesh size conservatively approximated the experimental deformation stresses while the machined bulk specimen tensionstress model over predicted the experimental stresses. On the other side, the strut stress model with 0.15 mm mesh size accurately predicted the experimental diagonal shear/fracture mode of struts with a slightly higher numerical initial peak stress. The compression tests on the strut specimens extracted from the as-built lattices yielded similar stress model parameters with the micro-tension tests. The differences between the initial peak stresses of the investigated sandwich and cubic lattices were further explained by the differences in the lattice boundary conditions.Article Citation - Scopus: 3Resurgent Dome and Super-Hot Enhanced Geothermal System: the Sahinkalesi Massif Within the Hasandag Stratovolcanic Province, Central Anatolia, Turkey(Elsevier B.V., 2024) Chandrasekharam,D.; Singh,M.; Baba,A.; Sass,I.The Sahinkalesi, a volcanic dome located NNE of Hasandağ, Türkiye exhibits anomalous heat flow value, geothermal gradient and the Curie point depth is located at very shallow depth in this region. Our investigation indicates presence of super-critical thermal regime (378°C) at about 4 km depth and the MT analysis indicate shallow magma chamber at about 5 km depth. The crust is relatively thin below this region with the low-velocity region located at depth of about 36 km. Thermo-Hydro-mechanical model investigation has been carried out using finite element discretization technique. For faulted zone reservoir models, 30 years of geothermal energy exploitation does not cause thermal breakthrough for mass flow rates up to 500 kg/s, however, the mean stress developed in the reservoir becomes much larger and may be unsustainable for the reservoir stability. To ensure the success of a fractured reservoir model, the use of multiple wellbores is recommended. In the case of a closed-loop geothermal system, the primary concern is the control of thermoelastic stress. This can be achieved either by increasing the wellbore depth while reducing the injection mass flow rate, or by extending the wellbore's horizontal component. The outlet temperature in both the cases maintained at 275°C. This is the first time a superhot EGS site has been identified in Türkiye. © 2024 The Author(s)Conference Object Citation - Scopus: 2Crystal Plasticity Based Modelling of Shear Response of Carbon Fibre Reinforced Composites(Elsevier B.V., 2021) Dizman,E.A.; Özdemir,I.Due to their superior strength-to-weight performance, there is an increasing tendency to use carbon fibre reinforced composites (CFRP) in different engineering applications. Under transverse loading, the resulting stress-strain curve has a nonlinear character with significant hardening. As far as modelling of CFRP is concerned, the hardening behaviour is typically described by fitting curves to experimental data. Obviously, this route does not take deformation mechanisms at constituent level e.g. fibre rotation and matrix yielding, into account and leads to descriptive models rather than predictive ones. Such models yield poor predictions particularly for CFRP's with 3D microstructural architectures, which have achieved much higher ductility level and texture evolution as compared to conventional 2D architectures. In recent studies Meza et al. (2019), Tan and Liu (2020), motivated by the similarity between the shearing along slip planes and the plastic deformation of a tow, crystal plasticity is exploited to capture the evolution of the composite microstructure. This contribution focuses on the crystal plasticity inspired model of CFRP and its implementation within the commercial finite element software Abaqus through UEL subroutine. The predictions of the model are assessed by means of two example problems including combined loading scenarios. © 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0) Peer-review under responsibility of IWPDF 2021 Chair, Tuncay YalçinkayaArticle Citation - Scopus: 50Observation of Electroweak Production of Wγ With Two Jets in Proton-Proton Collisions at S=13 Tev(Elsevier B.V., 2020) Sirunyan,A.M.; Tumasyan,A.; Adam,W.; Ambrogi,F.; Bergauer,T.; Dragicevic,M.; Chistov,R.A first observation is presented for the electroweak production of a W boson, a photon, and two jets in proton-proton collisions. The W boson decays are selected by requiring one identified electron or muon and an imbalance in transverse momentum. The two jets are required to have a high dijet mass and a large separation in pseudorapidity. The measurement is based on data collected with the CMS detector at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb−1. The observed (expected) significance for this process is 4.9 (4.6) standard deviations. After combining with previously reported CMS results at 8 TeV, the observed (expected) significance is 5.3 (4.8) standard deviations. The cross section for the electroweak Wγjj production in a restricted fiducial region is measured as 20.4±4.5fb and the total cross section for Wγ production in association with 2 jets in the same fiducial region is 108±16fb. All results are in good agreement with recent theoretical predictions. Constraints are placed on anomalous quartic gauge couplings in terms of dimension-8 effective field theory operators. © 2020 The Author(s)Article Citation - WoS: 4Citation - Scopus: 4Novel Electrospun-Based Extractive Probes for Rapid Determination of Clinically Important Compounds in Human Plasma(Elsevier B.V., 2024) Temel,E.R.; Eroğlu,A.E.; Salih,B.; Boyaci,E.Background: Coated blade spray (CBS) represents an innovative approach that utilizes solid-phase microextraction principles for sampling and sample preparation. When combined with ambient mass spectrometry (MS), it can also serve as an electrospray ionization source. Therefore, it became a promising tool in analytical applications as it can significantly reduce the analysis time. However, the current CBS coatings are based on the immobilization of extractive particles in bulk polymeric glue, which constrains the diffusion of the analytes to reach the extractive phase; therefore, the full reward of the system cannot be taken at pre-equilibrium. This has sparked the notion of developing new CBS probes that exhibit enhanced kinetics. Results: With this aim, to generate a new extractive phase with improved extraction kinetics, poly(divinylbenzene) (PDVB) nanoparticles were synthesized by mini-emulsion polymerization and then immobilized into sub-micrometer (in diameter) sized polyacrylonitrile fibers which were obtained by electrospinning method. Following the optimization and characterization studies, the electrospun-coated blades were used to determine cholesterol, testosterone, and progesterone in plasma spots using the CBS-MS approach. For testosterone and progesterone, 10 ng mL−1 limits of quantification could be obtained, which was 200 ng mL−1 for cholesterol in spot-sized samples without including any pre-treatment steps to samples prior to extraction. Significance: The comparison of the initial kinetics for dip-coated and electrospun-coated CBS probes proved that the electrospinning process could enhance the extraction kinetics; therefore, it can be used for more sensitive analyses. The total analysis time with this method, from sample preparation to instrumental analysis, takes only 7 min, which suggests that the new probes are promising for fast diagnostic applications. © 2024 Elsevier B.V.Article Citation - WoS: 13Citation - Scopus: 12Dunaliella Salina Microalgae Aqueous Extract-Based Magnetic Nanoparticles (fe3o4-Nps): Green Synthesis, Characterization and in Vitro Anticancer Investigations(Elsevier B.V., 2024) Jafari,N.; Hamishehkar,H.; Mohammadpourfard,M.In the current study, a facile, rapid, and eco-friendly method was provided for green synthesizing of magnetic Fe3O4-NPs with enhanced stability and biocompatibility using different weight concentrations (1 %, 3 %, and 5 %) of aqueous extract of Dunaliella salina (D. salina) microalgae. The properties of the green-synthesized magnetic nanoparticles (GMNPs-ex1%, GMNPs-ex3%, and GMNPs-ex5%) were compared with chemically-synthesized ones (CMNPs) via XRD, TEM, FESEM, VSM, DLS, ZP, FTIR, hemolysis, cell viability, DAPI staining, and apoptosis analyses. TEM imaging revealed mean sizes of 11.21 ± 2.63 nm and 14.08 ± 3.24 nm for GMNPs-ex5% and CMNPs, respectively, with better dispersity for GMNPs-ex5%, as confirmed with their polydispersity index (PDI = 0.24 for GMNPs-ex5% and 0.58 for CMNPs). These sizes were consistent with the crystallite size of pure magnetite phase nanoparticles obtained from XRD. FESEM images confirmed spherical shape for the majority of nanoparticles. FTIR spectra confirmed the involvement of functional groups from the extract in GMNPs, contributing to their stability (ZP of GMNPs-ex5% = −34 mV). The saturation magnetization decreased with increasing the extract ratio (from 62.41 to 8.94 emu/g), attributed to the non-magnetic nature of the extract coating. GMNPs-ex5% exhibited a negligible hemolysis rate (< 2 %) compared to CMNPs. Furthermore, IC50 values of GMNPs and extract against HFF-2 and A549 cells were higher than those of CMNPs, indicating the biocompatibility of green-synthesized nanoparticles. In the DAPI staining method, GMNPs-ex5%, similar to the extract, caused less DNA damage to HFF-2 cells. Additionally, the apoptosis assay using annexin V/PI staining kit indicated that green-synthesized nanoparticles induced lower apoptosis in normal cells. Overall, this study highlights the potential of green-synthesized Fe3O4-NPs for various biomedical applications, showcasing their enhanced properties and biocompatibility compared to conventionally synthesized counterparts. © 2024 Elsevier B.V.Article Effects of Edge Addition or Removal on the Nullity of a Graph(Elsevier B.V., 2024) Batal,A.Lights Out is a game which can be played on any graph G. Initially we have a configuration which assigns one of the two states on or off to each vertex. The aim of the game is to turn all vertices to off state for an initial configuration by activating some vertices where each activation switches the state of the vertex and all of its neighbors. If the aim of the game can be accomplished for all initial configurations then G is called always solvable. We call the dimension of the kernel of the closed neighborhood matrix of the graph over the field Z2, nullity of G. It turns out that G is always solvable if and only if its nullity is zero. Moreover, the number of solutions of a given configuration is also determined by the nullity. We investigate the problem of how nullity changes when an edge is added to or removed from a graph. As a result we show that for every graph with positive nullity there exists an edge whose removal decreases the nullity. Conversely, we show that for every always solvable graph which is not an even graph with odd order, there exists an edge whose addition increases the nullity. We also show that if an always solvable graph is not even, then there is an edge whose removal increases the nullity. © 2024Article Citation - WoS: 10Citation - Scopus: 11Arabinoxylan-Based Psyllium Seed Hydrocolloid: Single-Step Aqueous Extraction and Use in Tissue Engineering(Elsevier B.V., 2024) Yildirim-Semerci,Ö.; Bilginer-Kartal,R.; Arslan-Yildiz,A.Biomacromolecules derived from natural sources offer superior biocompatibility, biodegradability, and water-holding capacity, which make them promising scaffolds for tissue engineering. Psyllium seed has gained attention in biomedical applications recently due to its gel-forming ability, which is provided by its polysaccharide-rich content consisting mostly of arabinoxylan. This study focuses on the extraction and gelation of Psyllium seed hydrocolloid (PSH) in a single-step water-based protocol, and scaffold fabrication using freeze-drying method. After characterization of the scaffold, including morphological, mechanical, swelling, and protein adsorption analyses, 3D cell culture studies were done using NIH-3 T3 fibroblast cells on PSH scaffold, and cell viability was assessed using Live/Dead and Alamar Blue assays. Starting from day 1, high cell viability was obtained, and it reached 90 % at the end of 15-day culture period. Cellular morphology on PSH scaffold was monitored via SEM analysis; cellular aggregates then spheroid formation were observed throughout the study. Collagen Type-I and F-actin expressions were followed by immunostaining revealing a 9- and 10-fold increase during long-term culture. Overall, a single-step and non-toxic protocol was developed for extraction and gelation of PSH. Obtained results unveiled that PSH scaffold provided a favorable 3D microenvironment for cells, holding promise for further tissue engineering applications. © 2024 Elsevier B.V.Article Citation - WoS: 3Citation - Scopus: 3Macroporous Polymer-Derived Ceramics Produced by Standard and Additive Manufacturing Methods: How the Shaping Technique Can Affect Their High Temperature Thermal Behavior(Elsevier B.V., 2024) Zambotti,A.; Kulkarni,A.; Semerci,T.; Vakifahmetoglu,C.; Pelanconi,M.; Bottacin,S.; Sorarù,G.D.This work proposes the processing of porous ceramic lattices via three polymer-derived ceramic routes, namely powder bed fusion and infiltration, fused filament fabrication and replica, and a direct replica of a foamed polymer. A common feature in the processing of these lattices is the use of the same polysilazane as the preceramic source for the Si-C-N-O network that builds up during ceramization. We adopted rotated cube, honeycomb and randomized cellular geometries as a matter of comparison for thermal exchange when an air flow is forced through the structures up to 1050 °C. The three procedural pathways are discussed in their limitations regarding geometry, polymer-to-ceramic conversion, high-temperature heat exchange performance and durability. In this regard, while rotated cube geometry results in the best thermal exchange and highest pressure drop, we show a correlation between chemical composition and high temperature oxidation of the Si-C-N-O network, possibly attributed to the selection of the processing routes. © 2024 The AuthorsArticle Citation - WoS: 3Citation - Scopus: 4Caffeic Acid Phenethyl Ester (cape) Chitosan Capped Zno Nanoparticles: Preparation, Characterization, and Its Potential for the Treatment of Prostate Cancer(Elsevier B.V., 2024) İnce,İ.; Yıldırım,Y.; Göker,E.; Güler,G.; Saltan,F.; Acar,R.; Medine,E.İ.The synthesis of zinc oxide nanoparticles/chitosan (ZnONPs/CS) formulation loaded with Caffeic acid phenethyl ester (CAPE) was performed to evaluate its prostate cancer treatment efficiency within the scope of this research. It has been hypothesized that a dual active materials delivery system containing ZnO and CAPE loaded Chitosan (CS) nanoparticles has better bioavailability compared to single one against to cancer cells. ZnONPs were synthesized between 45 and 60 nm particle sizes and then they were capped with CS biodegradable polymer prior to load with CAPE bioactive molecule. ZnONPs/CS-CAPE system was characterized by using Fourier Transform Infrared (FTIR) for structural elucidation, Scanning Electron Microscope (SEM) for particle size determination, High Performance Liquid Chromatography (HPLC) system for determination of CAPE amount. 131I CAPE and 131I ZnONPs/CS-CAPE labeled by the Iodogen method with 131I were used in-vitro cell culture experiments. Cell viabilities (%) of CAPE and ZnONPs/CS-CAPE were examined using Cell Counting Kit-8 assay on PC-3 (human adenocarcinoma prostate), LnCaP (human carcinoma prostate), and RWPE-1 (human normal prostate). IC50 values of ZnONPs /CS -CAPE on all cells were found 2-fold lower than neat CAPE. Based on the FTIR data, the most significant spectral changes (lipid, protein, nucleic acids, glycogen) were monitored for the PC-3 and LnCaP cancer cells incubated with ZnONPs/CS-CAPE samples while being exposed to neat CAPE molecules caused small cellular changes when compared to RWPE-1 healthy cell lines. © 2024