WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collection

Permanent URI for this collectionhttps://hdl.handle.net/11147/7150

Browse

Filters

Settings

Publication Index: search.filters.publicationIndex.ScopusWoS Q: search.filters.wosQuartile.N/A

Search Results

Now showing 1 - 10 of 697
  • Article
    Brewing Property in Onedimensional City? Exploring Starbucks' Locational Strategies-Impacts in the Case of Izmir, Türkiye
    (University Cueca, 2026) Coskun, Yagmur Asci; Penpencioglu, Mehmet
    The article examines Starbucks'locational strategies and their impact on urban spaces, drawing on Rossi's concept of the "one-dimensional city." As global brands increasingly shape urban environments, three key effects emerge: rising property prices near stores, the concentration of locations in malls, transit hubs, and walkable areas, and alignment with urban landscapes standardized by major transportation infrastructure decisions. Similar to many cities in the Global South, Starbucks in & Idot;zmir functions both as a product and a driver of property-driven, rent-seeking urban development.Empirical evidence reveals that its locational strategies enhance accessibility, increase property values, and reshape the built environment. Through spatial analysis, the article examines Starbucks locations within a walkability and accessibility framework, highlighting their concentration in high-value districts with strong public transit connections.This research underscores how global brands reinforce socio-economic divides, transform urban spaces, and promote consumption-driven urbanization through their integration into global capitalism and real estate dynamics.
  • Article
    Interaction of Hazelnut-Derived Polyphenols With Biodegradable Film Matrix: Structural, Barrier, and Functional Properties
    (Multidisciplinary Digital Publishing Institute (MDPI), 2026) Hızır-Kadı, I.; Demircan, E.; Özçelik, B.
    The study presents a sustainable approach to valorizing hazelnut processing by-products, specifically skins and shells, through their conversion into bioactive polyphenol-rich extracts using pressurized hot water extraction (PHWE), an environmentally friendly green technology. PHWE yielded extracts with total phenolic contents of 25.4 mg GAE/g dw (shell) and 83.7 mg GAE/g dw (skin), which were incorporated into biodegradable poly(vinyl alcohol)/carboxymethyl cellulose (PVA/CMC) films at concentrations of 1–3% (w/v). The resulting composites were comprehensively characterized in terms of structural, mechanical, thermal, and barrier properties. FTIR, DSC, and XRD analyses demonstrated strong hydrogen bonding, increased thermal stability, and reduced crystallinity due to polyphenol–polymer interactions. Phenolic incorporation enhanced UV-blocking capability, increased antioxidant activity by up to five-fold, and reduced oxygen permeability from 0.048 to 0.015 (cm3·mm·m−2·day−1·atm−1) (69% reduction, p < 0.05), compared to neat PVA while maintaining desirable transparency (>70%). Optimal formulations (HSkE-II) exhibited a 39% increase in elongation at break and improved flexibility without compromising film integrity. Application tests using fresh-cut apples, watermelon, and chicken revealed significant reductions in microbial growth (up to ~1.2 log CFU/g), lipid oxidation, and weight loss during storage, confirming the films’ potential for active food packaging. This work highlights an efficient valorization strategy for nut industry by-products and demonstrates their functional integration into sustainable biodegradable packaging systems. © 2025 by the authors.
  • Article
    A Study of the Environmental Challenges En Marche Towards Net-Zero: Case Study of Turkish Steel Industry
    (Multidisciplinary Digital Publishing Institute (MDPI), 2026) Özdamar, A.B.; Kaya, M.; Bektas, A.; Bhattacharyya, S.; Şahindoğan, M.; Birat, Jean-Pierre; Dutta, A.
    The Turkish steel industry aims to reduce its sectoral carbon dioxide (CO<inf>2</inf>) emissions by 55% by 2030, in line with Türkiye’s Paris Agreement commitments and the European Green Deal (EGD), and consistent with the ambition of the European Union’s economy-wide ‘Fit for 55’ emissions-reduction target. Türkiye faces significant challenges in achieving net-zero greenhouse gas (GHG) emissions, particularly as a developing country confronting the impacts of climate change and in the market situation, such as the effects of the ongoing Russia-Ukraine conflict, limited access to affordable raw materials, and rising operational costs. This study serves as a guideline for the Turkish steel sector’s roadmap towards modernization and eventual compliance with net-zero targets. The consideration and integration of new technologies planned for the Turkish steel industry, in both electric arc furnace (EAF) and blast furnace-basic oxygen furnace (BF-BOF) facilities, have been outlined in conjunction with green hydrogen and with Carbon Capture and Storage (CCS) technologies. Four different scenarios were analysed to understand the reduction in CO<inf>2</inf> emissions: (1) In a Business-As-Usual (BAU) scenario without any reduction, (2) 39.9% CO<inf>2</inf> emission reduction with the Moderate scenario, (3) 59.6% reduction with the Advanced scenario, and (4) 82.9% reduction in CO<inf>2</inf> emissions from the Turkish steel sector with the Net-Zero scenario. To quantify the uncertainty in these long-term projections, a Monte Carlo simulation was conducted, generating probabilistic confidence intervals that reinforce the robustness and credibility of the net-zero pathway. The official roadmap for the sector is not available as of today; however, an in-depth discussion with a policy innovation leading to it is the objective of this study. © 2026 by the authors.
  • Article
    Completeness Relation in Renormalized Quantum Systems
    (Frontiers Media SA, 2025) Erman, F.; Turgut, O.T.
    In this work, we show that the completeness relation for the eigenvectors, which is an essential assumption of quantum mechanics, remains true if the Hamiltonian, having a discrete spectrum, is modified by a delta potential (to be made precise by a renormalization scheme) supported at a point in two- and three-dimensional compact manifolds or Euclidean spaces. The formulation can be easily extended to an (Formula presented.) center case and the case where delta interaction is supported on curves in the plane or space. We finally give an interesting application for the sudden perturbation of the support of the delta potential. © © 2025 Erman and Turgut.
  • Article
    Efficacy of Fermented Foods for the Prevention and Treatment of Bacterial Vaginosis and Vulvovaginal Candidiasis
    (Frontiers Media SA, 2025) Akpinar, A.; Markiewicz, L.H.; Harsa, H.S.; Paveljšek, D.; Domínguez-Soberanes, J.; Agirbasli, Z.; Karakaş-Budak, B.
    Vaginal function in healthy women is closely associated with a lactobacilli-dominated microbiome. Among the most common conditions arising from dysbiosis are bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC). While the efficacy of oral probiotics for the treatment of BV and VVC is well documented, the role of consuming fermented foods remains underexplored. This systematic review aims to present a systematic evaluation of the potential role of fermented foods in the prevention and treatment of BV and VVC and establish the extant research gap between the realm of the clinical sciences and the field of food science and technology. For this purpose, under the guidance of COST Action CA20128—Promoting Innovation of Fermented Foods (PIMENTO), a systematic literature review was conducted in two phases. PubMed, Scopus, and Cochrane databases were used for Phase I to analyze articles on human trials and observational studies where the intervention/exposure involved oral consumption of fermented food. In Phase II, a two-step search strategy was employed: (i) identifying microorganisms with demonstrated clinical efficacy in managing BV and VVC, and (ii) reviewing food science literature where these strains are utilized for fermentation. It was observed that 87% of the food starter applications exploited only two of the 54 efficacious strains identified through clinical studies, namely Lactobacillus rhamnosus GG and Lactobacillus acidophilus LA-5. Findings underscore the potential of fermented foods as carriers for beneficial microorganisms and their relevance in supporting vaginal health. This review contributes to a deeper understanding of the interplay between nutritional consumption of viable probiotic strains and their importance in immunomodulation, highlighting the need for more integrated research efforts across disciplines. Future research aimed at filling this gap will enable informed clinical decisions and dietary recommendations. © © 2025 Akpınar, Markiewicz, Harsa, Paveljšek, Domínguez-Soberanes, Agirbasli, Naziri, El Jalil, Bouchaud, Salminen, Savary-Auzeloux, Humblot, Chassard, Pracer, Vergères and Karakaş-Budak.
  • Article
    Tuning Pore Chemistry in Dioxin-Linked Porous Organic Polymers for Enhanced High-Pressure CO2 Uptake
    (John Wiley and Sons Inc, 2025) Ashirov, T.; Piech, K.; Büyükcakir, O.; Yildirim, T.; Coskun, A.
    Precise tuning of pore chemistry in three-dimensional porous organic polymers (3D-POPs) is critical for high-performance gas (CO<inf>2</inf>)-separation. Here, we demonstrate the impact of functional groups on the dioxin-linked 3D-tPOPs bearing a tetraphenylene core, synthesized under solvothermal conditions using NaCl as a template, on the low- and high-pressure CO<inf>2</inf> uptake. The post-synthetic amidoxime functionalization of 3D-tPOPs, involving the reaction of pendant nitrile moieties with hydroxylamine hydrochloride, has been shown to precisely tailor pore chemistry without altering the network structure. Whereas the incorporation of the amidoxime moieties, 3D-tPOP-AO, enables higher heteroatom content, a critical factor to enhance CO<inf>2</inf> affinity at low pressures, strong hydrogen bonding interactions between amidoxime units limit framework flexibility, thus leading to a significant decrease in the high-pressure gas uptake. 3D-tPOPs on the other hand showed a high CO<inf>2</inf> uptake capacity of 57.4 wt% at 33 bar and 270 K; after modification, CO<inf>2</inf> uptake capacity decreased to 19.4 wt% at 273 K and 34 bar. Similarly, CH<inf>4</inf> uptake capacity also decreased from 14.0 wt% at 116 bar and 270 K to 3.8 wt% at 75 bar and 273 K. These findings highlight the critical role of the interactions between functional groups and pore chemistry to form robust adsorbents with high CO<inf>2</inf> uptake performance at high pressures. © 2025 The Author(s). Helvetica Chimica Acta published by Wiley-VHCA AG.
  • Article
    Chemosensitizing Effect of Apigenin on T-ALL Cell Therapy
    (Frontiers Media SA, 2025) Huseynova, N.; Baran, Z.; Khalilov, R.; Mammadova, A.; Baran, Y.
    T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy with limited therapeutic options and frequent treatment-associated toxicities. L-asparaginase, a cornerstone in T-ALL therapy, is often restricted by hypersensitivity reactions and systemic side effects, highlighting the need for safer strategies to enhance its efficacy. This study investigated the potential of apigenin, a naturally occurring flavonoid with antioxidant and pro-apoptotic properties, to act as a chemosensitizer for L-asparaginase in MOLT-4 T-ALL cells. Cytotoxicity was assessed using the MTT assay, apoptosis by Annexin V/PI staining, cell cycle distribution by flow cytometry, and mitochondrial membrane potential by JC-1 staining. Both apigenin and L-asparaginase produced dose- and time-dependent cytotoxicity, with combination treatment resulting in reduced IC<inf>50</inf> values. Apoptotic analysis showed significantly higher apoptosis in the combination-treated groups than in single-agent groups. Cell cycle analysis revealed that apigenin induced S-phase arrest and L-asparaginase induced G1-phase arrest, while the combination disrupted cell cycle progression at multiple checkpoints. JC-1 assay further demonstrated enhanced mitochondrial depolarization, with up to a 29.2-fold increase in cytoplasmic-to-mitochondrial fluorescence ratio in combination therapy compared to L-asparaginase alone. These findings indicate that apigenin potentiates L-asparaginase-induced cytotoxicity through mitochondrial dysfunction and intrinsic apoptotic signaling. The combined use of apigenin and L-asparaginase may provide a novel strategy to improve therapeutic efficacy in T-ALL while potentially reducing the toxicity associated with high-dose L-asparaginase monotherapy. © © 2025 Huseynova, Baran, Khalilov, Mammadova and Baran.
  • Article
    Sandwich-Structured Coating for Ultraviolet Protection and Thermal Management Applications
    (American Chemical Society, 2025) Kartal, U.; Yurddaskal, M.
    During the day, exposure to UV radiation poses risks to human health, while managing heat exchange is important for comfort in protective textiles. Recently, infrared-reflective materials have attracted attention, particularly for reducing the infrared transmission and moderating the thermal emission. In this study, titanium dioxide/copper–aluminum/titanium dioxide (TiO<inf>2</inf>/Cu–Al/TiO<inf>2</inf>, TCAT) sandwich-structured coatings were deposited on polyester fabric using magnetron sputtering. Deposition times (40 and 90 s) were varied to adjust Al and Cu layer thicknesses between 20 and 55 nm, and the resulting films were characterized by X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, UV–vis spectroscopy, and thermal imaging. The coatings retained moderate visible transmittance on glass, whereas on woven polyester fabric, they formed an optically dense barrier with near-zero UV transmittance, suppressing light penetration across the visible to near-infrared (VIS–NIR) range. In conjunction with the emissivity-aware interpretation of thermography, these results substantiate substrate-independent UV shielding and optical/thermal barrier behavior of the TCAT multilayer. Thermal imaging qualitatively indicated reduced apparent surface temperature for coated fabrics compared to uncoated ones, suggesting partial thermal shielding. These results demonstrate the feasibility of integrating multifunctional coatings into daily-use polyester textiles, offering effective UV protection and the potential for thermal management in protective applications. © 2025 The Authors. Published by American Chemical Society
  • Article
    Rhythmanalysis of Istanbul Ayasofya's (re)mosquification During the COVID-19 Pandemic: A Diachronic Overview
    (Routledge Journals, Taylor & Francis Ltd, 2025) Akture, Zeynep; Kazanasmaz, Zehra Tugce
    Inauguration of the Grand Mosque of Ayasofya, Istanbul, in 2020 was among the cultural heritage-related magnet events of the COVID-19 pandemic period. This essay focuses on the impacts of function change on the monument's spatial experience, by tracing a continuity of change in its everyday life and use in a continuously changing urban context, through comparatively minor physical interventions starting with the 'necessary minimum' to its 'acupuncture points', as was done during its earlier mosquification and museumification, both of which (were) initiated (by) structural transformations in the longue dur & eacute;e. Following Henri Lefebvre's argument on spatiality of politics and history, and adopting his rhythmanalysis tool, significance of the recent function change is argued to reside in the resulting spatial experience that is characterised by spatiotemporally alternating and/or overlapping political, religious, and tourist 'rituals' that are conditioned by and conditioning longer-term structural changes. Concluding observations target future research along the proposed trajectory.
  • Conference Object
    Avoidance of Feature Configuration Faults in Software Product Lines
    (IEEE Computer Soc, 2025) Ergun, Burcu; Tuglular, Tugkan; Belli, Fevzi
    This paper presents a validation approach to feature selection in software product lines (SPL). SPLs consist of similar products tailored to different needs, while SPLs sharing a common platform where feature configurations define product families. Validating feature configurations is critical to avoid defective shipments, recalls, and disposal. Exhaustive, pairwise, and combinatorial testing, among others, aim at ensuring configuration correctness. This paper introduces a novel method for improving feature selection and validation in SPLs by minimizing redundancy while ensuring configurations align with customer needs. The method emphasizes uncovering the differences in feature structures through "complex" and "simple" models, which helps identify and helps identify and tolerate potential errors arising from incorrect feature configurations. This ensures broader coverage while effectively managing dependencies. A case study using the Access Point (AP) SPL model, which is a networking device designed to enhance the strength of an existing wireless signal and expand its coverage area. The AP can enable or disable specific features on AP SPL depending on the characteristics of the third-party gateway with which it is integrated. AP SPL model with 66 features lead to 266 configurations, generated by Exhaustive Testing. Pairwise testing achieves 87% coverage with 132 test cases, while combinatorial testing reaches 94% with 45,760 cases. Our method ensures 100% feature coverage with just 3 test configurations. Thus, the approach introduced in this paper enhances product quality while reducing costs by avoiding redundant tests, making the approaches valuable for large-scale SPLs.