Electrical - Electronic Engineering / Elektrik - Elektronik Mühendisliği
Permanent URI for this collectionhttps://hdl.handle.net/11147/11
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Conference Object Citation - Scopus: 2Parkinson hastalığı sınıflandırmasına yönelik ivmeölçer tabanlı zamanlama analizi(IEEE, 2023) Karaçalı, Bilge; Onay, FatihParkinson's disease is a neurodegenerative disorder caused by dopamine deficiency in the basal ganglia, resulting in cognitive and motor impairments. In this study, accelerometer signals were used to estimate the delay time between the command to start pedaling and the actual movement onset in three groups: healthy individuals (n=13), Parkinson's disease patients (n=13), and patients with freezing of gait symptoms (n=13). Features were extracted from the delay time distributions for each participant and subjected to a triple classification. Linear support vector machine achieved a classification accuracy of 69.2% for all participants. Notably, the average time to start pedaling was found to be significantly different among the three groups, and accelerometer-based timing analysis could be used as a diagnostic tool to assist clinical tests.Conference Object Algıda gecikme ve kısa-ömürlü senkronizasyon temelli yeni bir hayali motor aktivite tanıma yaklaşımı(IEEE, 2023) Olcay, B. Orkan; Karaçalı, BilgeThis study proposes a novel approach for investigating a brain-computer interface that considers the temporal organization of brain activity, explicitly accounting for perception latency. To this end, we aligned the onset of task periods with the concurrence of left parietal and parieto-occipital electrodes to obtain the timings of perception latencies. Then, activity-specific synchronization timings between channel pairs were calculated using the time-aligned task periods. The perception latency and activity-specific synchronization timings were subsequently used for feature extraction and classification. The proposed approach achieved significantly better performance when comparing the proposed approach with the method that did not account for the perception latencyConference Object Citation - Scopus: 2Model-Free Expectation Maximization for Divisive Hierarchical Clustering of Multicolor Flow Cytometry Data(IEEE, 2014) Köktürk, Başak Esin; Karaçalı, BilgeThis paper proposes a new method for automated clustering of high dimensional datasets. The method is based on a recursive binary division strategy that successively divides an original dataset into distinct clusters. Each binary division is carried out using a model-free expectation maximization scheme that exploits the posterior probability computation capability of the quasi-supervised learning algorithm. The divisions are carried out until a division cost exceeds an adaptively determined limit. Experiment results on synthetic as well as real multi-color flow cytometry datasets showed that the proposed method can accurately capture the prominent clusters without requiring any knowledge on the number of clusters or their distribution models.Conference Object Citation - Scopus: 1Dijital Sitolojide Kanser Tanıma için Analitik ve Öngörüsel Yarı-güdümlü Öğrenme(IEEE, 2012) Karaçalı, BilgeIn this work, cancer recognition in digital cytology data was carried out using quasi-supervised learning. The data subject to recognition contained ground-truth data only in the form of a labeled set of cancer-free samples and the cancerous samples were provided along with cancer-free samples in an unlabeled mixed dataset. In this framework, a predictive method was derived to label future samples as cancerous or cancer-free based on this data at hand together with an analytical method to label the cancerous samples in the mixed dataset. In the experiments, the methods based on the quasi-supervised learning algorithm achieved higher recognition performance in both cases than the alternative approaches based on supervised support vector machine classifiers. These results indicate that the quasi-supervised learning is the only valid approach in both analytical and predictive recognition when only labeled cancer-free samples are available for statistical learning. © 2012 IEEE.Conference Object Citation - Scopus: 1Elektroensefalografi Verilerinin Yarı-güdümlü Öğrenme ile Otomatik Olarak İşaretlenmesi(IEEE, 2012) Köktürk, Başak Esin; Karaçalı, BilgeIn this study, the separation of the stimulus effects from the baseline was investigated in electroencephalography data recorded under different visual stimuli using quasi-supervised learning. The data feature vectors were constructed using independent component analysis and wavelet transform, and then, these feature vectors were separated using quasi-supervised learning. Experiment results showed that the EEG data of the stimuli can be separated using quasi-supervised learning. © 2012 IEEE.Conference Object Farklı Kontrastlı Medi̇kal Görüntülerde Elasti̇k Hi̇zalama İ̇çi̇n Ni̇rengi̇ Noktalarının Beli̇rlenmesi̇ ve Sınanması(IEEE, 2011) Karaçalı, BilgeIn this study, automatic identification of landmarks was carried out on real double-echo PD/T2 Magnetic Resonance images for use in multi-modality deformable image registration algorithms. To this end, the corner points of the PD-weighted Magnetic Resonance image selected as the reference image were identified at varying fields of view and used as landmark candidates after eliminating the repeated points and those at close proximity. Next, the matching performances of these candidates were determined by invoking a localization algorithm that optimizes information theoretic point similarity measures derived earlier after random initialization at varying distances and directions. In consideration to the best performing point similarity measures and neighborhood radii at landmarks providing successful localization, the mutual information-based point similarity measure evaluated over large neighborhoods was preferred at a conspicuously higher rate than the other alternatives. © 2011 IEEE.Conference Object Citation - Scopus: 1Doğrusal Olmayan Gömme Teknikleri Altında Gen Dizilerinin Evrimsel İ̇lişkileri(IEEE, 2010) Doğan, Tunca; Karaçalı, BilgeWe present an error analysis on the application of non-linear embedding on pairwise evolutionary distances inferred over a collection of genetic sequences following multiple sequence alignment. To this end, we have generated gene sequences evolved by random substitutions along three different evolutionary pathways with known evolutionary distances between every sequence pair. We have compared the discrepancy between the inferred evolutionary distances to the true distances before and after non-linear embedding into a low dimensional vector space. The results indicate that non-linear embedding achieves significant reduction in error in the estimated evolutionary distances. Consequently, nonlinear embedding of evolutionary distances can provide more reliable inferences on the evolutionary relationships between genetic sequences. ©2010 IEEE.Conference Object Yönelimli Eşlenik Noktalar ile Deformasyon Alanı Ara Değerlemesi(IEEE, 2010) Karaçalı, BilgeIn this paper, we present a novel method for landmark-based deformation field interpolation that incorporates the rotation information for use in curved medical image registration applications. To this end, each Cartesian component of the interpolated deformation field was modeled by a mixture of Gaussian radial basis functions. The mixture coefficients were identified by optimizing an energy functional that seeks to match the landmark positions as well as the orientations of their neighborhoods. Optimization of this functional was carried out via a gradient descent strategy using the closedform expressions of the partial derivatives with respect to the Gaussian radial basis function coefficients. In the experiments, grater accuracy was observed in the estimation of the unknown deformation fields when the rotation information was incorporated in the interpolation. These results indicate that the proposed scheme can achieve greater accuracy in deformation field interpolation, especially in deformable alignment of multimodality medical images for which the landmarks have to be matched by taking into account the proper orientations of their neighborhoods. ©2010 IEEE.