Electrical - Electronic Engineering / Elektrik - Elektronik Mühendisliği
Permanent URI for this collectionhttps://hdl.handle.net/11147/11
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Article Citation - WoS: 7Citation - Scopus: 10Analysis of Crosstalk Effects in Phase-Otdr System Using Fiber Bragg Grating Array(Elsevier, 2023) Koçal, Ertunga Burak; Yüksel, Kıvılcım; Wuilpart, MarcIn this paper, the parasitic components (i.e., multi-reflections, Rayleigh scattering, photodetector noise, and phase variations due to external perturbations) are analysed and based on this analysis, a new signal to noise ratio (SNR) definition is provided suitable for the FBG-assisted Phase-OTDR system. A detailed analysis of performance parameters in the presence of multi reflection crosstalk (including its first- and second-order components) and spectral shadowing crosstalk is presented. SNR was calculated for different reflectivity and spacing lengths showing that the maximum number of cascaded FBGs can be significantly increased by using lower FBG reflectivity. It was also observed that the spacing length distance does not have a significant impact on the maximum number of FBGs that can be interrogated. By comparing single-pulse and double-pulse configurations, the use of double pulse was shown to provide higher SNR values when the number of FBGs is around 100 FBGs. The multi-reflection crosstalk when combined with the spectral-shadowing effect was demonstrated to create secondary crosstalk components making the interpretation of spectral analysis more difficult.Article Citation - WoS: 3Citation - Scopus: 3Current Sensing Using a Phase-Sensitive Optical Time Domain Reflectometer: Feasibility Study(Elsevier, 2022) Wuilpart, Marc; Şirin, Şamil; Yüksel Aldoğan, KıvılcımA novel method for distributed current sensing using an FBG-assisted Phase-OTDR with Mach-Zehnder Interferometer is proposed. The detrimental effect of the intrinsic linear birefringence of the sensing fiber is solved by calibration. An FBG pair is written at the two ends of the spun fiber coil to eliminate phase fading and increase the measurement accuracy. A simulation tool was developed to reveal the feasibility of the approach by investigating the impact of the detector noise as well as the effects of bending- and FBG-induced linear birefringence on the sensing performance.Article Citation - WoS: 6Citation - Scopus: 10Surface Chemistry Dependent Toxicity of Inorganic Nanostructure Glycoconjugates on Bacterial Cells and Cancer Cell Lines(Elsevier, 2023) Sancak, Sedanur; Yazgan, İdris; Bayarslan, Aslı Uğurlu; Ayna, Adnan; Evecen, Senanur; Taşdelen, Zehra; Gümüş, Abdurrahman; Sönmez, Hamide Ayçin; Demir, Mehmet Ali; Demir, Sosin; Bakar, Fatma; Dilek Tepe, HafizeSurface functionalized nanostructures have outstanding potential in biological applications owing to their target-specific design. In this study, we utilized laboratory synthesized carbohydrate-derivatives (i.e., galactose, mannose, lactose, and cellobiose derivatives) for aqueous one-pot synthesis of gold (Au) and silver (Ag) nanostructure glycoconjugates (NSs), and iron metal-organic framework glycoconjugates (FeMOFs). This work aims to test whether differences in the surface chemistry of the inorganic nanostructures play roles in revealing their toxicities towards bacterial cells and cancerous cell lines. As of the first step, biological activity of AuNSs, AgNSs, and FeMOFs were tested against a variety of gram (−) and gram (+) bacterial strains, where AgNSs possessed moderate to high antibacterial activities against all the tested bacterial strains, while AuNSs and FeMOFs showed their bacterial toxicity mostly depending on the strain. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) determination studies were performed for the nanostructure glycoconjugates, for which μg/mL MBC values were obtained such as (Cellobiose p-aminobenzoic acid_AgNS) CBpAB_AgNS gave 50 μg/mL MBC value for P.aeruginosa and S.kentucy. The activity of selected sugar ligands and corresponding glycoconjugates were further tested on MDA-MB-231 breast cancer and A549 lung cancer cell lines, where selective anticancer activity was observed depending on the surface chemistry as well. Besides, D-penicillamine was introduced to galectin specific sugar ligand coated AuNS glycoconjugates, which showed very strong anticancer activities even at low doses. Overall, the importance of this work is that the surface chemistry of the inorganic nanostructures can be critical to reveal their toxicity towards bacterial cells and cancerous cell lines.