Chemistry / Kimya

Permanent URI for this collectionhttps://hdl.handle.net/11147/4072

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  • Article
    Citation - WoS: 3
    Citation - Scopus: 3
    Roadmap on Multifunctional Materials for Drug Delivery
    (IOP Publishing, 2024) Nottelet, Benjamin; Buwalda, Sytze; van Nostrum, Cornelus F.; Zhao, Xiaofei; Deng, Chao; Zhong, Zhiyuan; Cheah, Ernest; Kehr, Nermin Seda
    This Roadmap on drug delivery aims to cover some of the most recent advances in the field of materials for drug delivery systems (DDSs) and emphasizes the role that multifunctional materials play in advancing the performance of modern DDSs in the context of the most current challenges presented. The Roadmap is comprised of multiple sections, each of which introduces the status of the field, the current and future challenges faced, and a perspective of the required advances necessary for biomaterial science to tackle these challenges. It is our hope that this collective vision will contribute to the initiation of conversation and collaboration across all areas of multifunctional materials for DDSs. We stress that this article is not meant to be a fully comprehensive review but rather an up-to-date snapshot of different areas of research, with a minimal number of references that focus upon the very latest research developments.
  • Article
    Citation - WoS: 36
    Citation - Scopus: 38
    Investigation on Glassy Skin Formation of Porous Polystyrene Fibers Electrospun From Dmf
    (BME-PT, 2010) Demir, Mustafa Muammer
    Micrometer and submicrometer diameter of polystyrene (PS) fibers were electrospun from various dimethyl formamide (DMF) solutions at different weight fractions under 35% relative humidity. Increasing polymer fraction in the solution results in a gradual morphological transition from beads-with-incipient to bead-free fibers and also increases the diameter. The formation of uniform glassy skin presumably due to radial capillary flow within the liquid jet was confirmed by scanning electron microscope. The thickness of the skin varies with the weight fraction of PS; therefore, it was normalized with respect to average fiber diameter (AFD). The skin gets thinner as the weight fraction of PS increases. In addition, the fibers exhibit highly porous internal structure and smooth surface along with slight porosity. The development of porosity is attributed to liquid-liquid phase separation of water molecules in atmospheric moisture and DMF.