Bioengineering / Biyomühendislik

Permanent URI for this collectionhttps://hdl.handle.net/11147/4529

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Author: search.filters.author.Duman, SedaSubject: search.filters.subject.Astragalus

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  • Article
    Citation - WoS: 27
    Citation - Scopus: 30
    Biotransformation of Cyclocanthogenol by the Endophytic Fungus Alternaria Eureka 1e1bl1
    (Elsevier Ltd., 2018) Ekiz, Güner; Duman, Seda; Bedir, Erdal
    The microbial transformation of cyclocanthogenol (CCG), Astragalus sp. originated sapogenin, by the endophytic fungus Alternaria eureka 1E1BL1 isolated from Astragalus angustifolius was investigated. Hydroxylation, oxidation, epoxidation, O-methylation, ring-expansion and methyl migration reactions were observed on the triterpenoid skeleton. As a result, eight metabolites were isolated and the structures of the previously undescribed compounds were established by 1-D, 2-D NMR and HR-MS analyses.