Emrullahoğlu, Mustafa
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Emrullahoğlu, M
Emrullahoglu, M
Emrullahoglu, Mustafa
Emrullahoğlu, M.
Emrullahoglu, M.
Emrullahoglu, M
Emrullahoglu, Mustafa
Emrullahoğlu, M.
Emrullahoglu, M.
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Email Address
mustafaemrullahoglu@iyte.edu.tr
Main Affiliation
04.04. Department of Photonics
Status
Current Staff
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Sustainable Development Goals
1NO POVERTY
0
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2ZERO HUNGER
1
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3GOOD HEALTH AND WELL-BEING
2
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4QUALITY EDUCATION
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5GENDER EQUALITY
0
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6CLEAN WATER AND SANITATION
2
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7AFFORDABLE AND CLEAN ENERGY
4
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8DECENT WORK AND ECONOMIC GROWTH
1
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9INDUSTRY, INNOVATION AND INFRASTRUCTURE
5
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10REDUCED INEQUALITIES
0
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11SUSTAINABLE CITIES AND COMMUNITIES
0
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12RESPONSIBLE CONSUMPTION AND PRODUCTION
2
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13CLIMATE ACTION
3
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14LIFE BELOW WATER
1
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15LIFE ON LAND
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16PEACE, JUSTICE AND STRONG INSTITUTIONS
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17PARTNERSHIPS FOR THE GOALS
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Documents
44
Citations
1638
h-index
23
Documents
40
Citations
1579
Scholarly Output
53
Articles
35
Views / Downloads
164910/24375
Supervised MSc Theses
15
Supervised PhD Theses
3
WoS Citation Count
1064
Scopus Citation Count
1101
Patents
0
Projects
10
WoS Citations per Publication
20.08
Scopus Citations per Publication
20.77
Open Access Source
41
Supervised Theses
18
| Journal | Count |
|---|---|
| Chemical Communications | 7 |
| Journal of Materials Science: Materials in Electronics | 3 |
| Chemistry - A European Journal | 2 |
| New Journal of Chemistry | 2 |
| ChemistrySelect | 1 |
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53 results
Scholarly Output Search Results
Now showing 1 - 10 of 53
Article Citation - WoS: 16Citation - Scopus: 16Investigation of Electrical and Photovoltaic Properties of Au/N-si Schottky Diode With Bod-Z Interlayer(Springer, 2021) Tezcan, Ali Osman; Eymur, Serkan; Taşcı, Enis; Emrullahoğlu, Mustafa; Tuğluoğlu, Nihat4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) based BOD-Z-EN compound was used as an interfacial organic layer to fabrication of Au/BOD-Z-EN/n-Si/In diode. The electrical parameters of Au/BOD-Z-EN/n-Si/In diode such as ideality factor (n), barrier height (phi(b)) and series resistance (R-s) have been investigated through current-voltage (I-V) studies at dark and under various illumination intensities to understand the effect of interlayer on the device properties. The values found for the n varied from 2.33 to 1.55 and the phi(b) ranged from 0.86 to 0.90 eV as the illumination condition changed from dark to 100 mW/cm(2). Series resistance (R-s) values calculated using Cheung's method were found to decrease with increasing illumination level. The forward bias I-V characteristics of the diode were explained by the space charge limited current theory. The main photovoltaic parameters such as open circuit voltage (V-oc), short circuit current density (J(sc)) and fill factor (FF) were determined for various light intensity. The Au/BOD-Z-EN/n-Si/In diode exhibits a photovoltaic behavior with a V-oc of 150 mV and J(sc) of 10 mu A/cm(2) under 100 mw/cm(2). In addition, photosensitivity and photoresponsivity properties of the diode were determined. All these results indicate that Au/BOD-Z-EN/n-Si/In device can be used as photosensor in optoelectronic applications.Master Thesis Design and Synthesis of Phosphine Based Fluorescent Probes for Reactive Oxygen Species(Izmir Institute of Technology, 2018) Üçüncü, Canan; Emrullahoğlu, Mustafa; Emrullahoğlu, MustafaHypochlorous acid is a cleansing agent known as bleach in daily life. Apart from the household chemicals feature, HOCl plays an active role in the defence system of living cells. It is an important reactive oxygen species that exhibits anti-microbial properties against invaders. However, the increase in the amount of cells in the cell due to oxidative stress causes serious damage to the structure and function of the organism and can cause fatal diseases. Determination of reactive oxygen species in the cell is of great importance. Although different detection methods are used for this purpose, fluorescent sensors are preferred for their precision, easy preparation, high resolution, and quick response. In this study, a "turn on" probe has been designed to detect HOCl based on these reasons. Anthracene dye has been found to be non-fluorescent due to PET when derivatized with phosphorus. In the presence of HOCl, it was determined that the phosphorus was oxidized, inhibiting PET and causing fluorescent radiation. The aim of this thesis is to examine the spectroscopic analysis of the probe which is developed as sensitive to HOCl in various ways and to display the presence of HOCl in the living cell.Article Citation - WoS: 23Citation - Scopus: 23Bodipy-Vinyl Dibromides as Triplet Sensitisers for Photodynamic Therapy and Triplet-Triplet Annihilation Upconversion(Royal Society of Chemistry, 2021) Dartar, Suay; Üçüncü, Muhammed; Karakuş, Erman; Hou, Yuqi; Zhao, Jianzhang; Emrullahoğlu, MustafaWe devised a new generation of halogen-based triplet sensitisers comprising geminal dibromides at the vinyl backbone of a BODIPY fluorophore. Incorporating geminal dibromides into the pi-conjugation of BODIPY enhanced intersystem crossing due to the heavy atom effect, which in turn improved the extent of excited triplet states.Article Citation - WoS: 60Citation - Scopus: 62A Bodipy-Based Reactive Probe for the Detection of Au(iii) Species and Its Application To Cell Imaging(Royal Society of Chemistry, 2014) Üçüncü, Muhammed; Emrullahoğlu, MustafaA BODIPY-based fluorescent probe bearing a pyridyl hydrazone motif responds selectively to Au(III) ions through an irreversible C[double bond, length as m-dash]N bond hydrolysis reaction. Gold species, besides their ability to catalyse chemical transformations in organic synthesis,1 have significant impacts on human health.2,3 Gold-based drugs have long been used in the treatment of rheumatoid arthritis and other autoimmune diseases.2 At the same time, when accumulated in the biological system at certain concentrations, gold species have the potential to disturb a series of cellular processes by irreversible interaction with biomolecules.3 In recent years, fluorescence-based sensing has become an indispensable tool for sensitive and accurate detection of trace levels of metal species in the solution.4 In addition, with the aid of fluorescence microscopy it has become possible to track metal species in living cells, which is of crucial importance for elucidating their roles in the biological system.Master Thesis Desing and Synthesis of Fluorescent Chemodosimeter for the Analysis of the Gold Ions(Izmir Institute of Technology, 2018) Çevik Eren, Merve; Emrullahoğlu, MustafaThe gold element has been used in many different areas throughout history. This includes the treatment of various diseases with drugs containing gold. In contrast to gold metal, gold ions are known to be extremely harmful to the human body. Therefore, the determination of the gold ions in the human body is very important. Gold ion determination can be made by using expensive spectroscopic methods. In contrast to highly expensive spectroscopic methods, chemosensors with high sensitivity and selectivity are a good option to make the gold determination. The bodipy fluorophore is a good example for the metal ion chemosensor. In this study, a bodipybased fluorescence sensor derived from a unique motif that has a triple bond was designed and synthesized. By activating the triple bond of the gold ions, it becomes selective to the gold ions as a result of ırreversible intramolecular cycling.Article Citation - WoS: 4Citation - Scopus: 4A Cyclopalladated Bodipy Construct as a Fluorescent Probe for Carbon Monoxide(Wiley, 2022) Çevik Eren, Merve; Eren, Ahmet; Dartar, Suay; Tütüncü, Büşra Buse; Emrullahoğlu, MustafaBy introducing a palladium ion into the backbone of BODIPY, we devised a cyclopalladated BODIPY construct that was almost non-emissive in the absence of any analyte but became highly fluorescent upon interacting with carbon monoxide (CO) in solution and in living cells. A process of ortho-carbonylation and depalladation mediated by the specific binding of CO to palladium, promoted the release of the heavy atom from the fluorophore and consequently generated a fluorescence signal with an exceptionally high (60-fold) enhancement ratio.Article Citation - WoS: 11Citation - Scopus: 13Electrical, Photodiode, and Dft Studies of Newly Synthesized Pi-Conjugated Bodipy Dye-Based Au/Bod-dim Device(Elsevier, 2021) Şahin, Muhammet Ferit; Taşcı, Enis; Emrullahoğlu, Mustafa; Gökçe, Halil; Tuğluoğlu, Nihat; Eymur, SerkanA pi-conjugated 4,4-difluoro-4- bora-3a,4a-diaza-s-indacene (BODIPY) dimer (BOD-Dim) compound has been synthesized and characterized. The optimized molecular structure, the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) simulations, and static isotropic polarizability of the isolated compound were computed via the Gaussian program. The simulated static dielectric constant value was calculated. The effect of the BOD-Dim interlayer on the diode characteristics of the Au/n-Si diode was investigated. The electrical and photovoltaic parameters of the Au/BOD-Dim/n-Si/In diode such as ideality factor (n), barrier height (phi B), open-circuit voltage (Voc), short-circuit current (Jsc), photosensitivity (S), and photoresponsivity (R) have been investigated by current-voltage measurements at dark and under various illumination intensities. The possible current conduction mechanism has been examined through the forward bias ln (IF)-ln(VF) and ln(IR)-VR1/2 characteristics. All obtained results confirmed that Au/BOD-Dim/n-Si/In diode exhibits a photovoltaic behavior and presents great potential as a photosensor for optoelectronic device applications.Master Thesis Study of Drug Transportation by Esr Spectroscopy(Izmir Institute of Technology, 2018) Tatlıdil, Duygu; Akdoğan, Yaşar; Emrullahoğlu, MustafaThe ability to track drug binding and release makes electron spin resonance (ESR) spectroscopy well suited for drug delivery studies. Using the continuous wave cw ESR technique to extract information about the dynamics of the spin labeled drugs we can simultaneously determine the bound and unbound drugs. In this study, ESR technique was used to detect the binding and release of spinlabeled salicylic acid (SLSA) to and from bovine serum albumin (BSA), and to detect different binding interactions between them. We have labeled salicylic acid with stable nitroxide-based tempo radicals to monitor the BSA bound and unbound conditions of the drug. Studying with the different concentrations of SLSA-BSA binding showed that the drug-protein stoichiometry increases significantly in the physiological range of BSA concentration. Also, during the release of SLSA from BSA, there is an unchanging balance between the bound and unbound SLSA. In order to study various drug binding interactions, SL-benzoic acid, SL-phenol, SL-benzene, SL-cyclohexane, SL-hexane and SL-methyl were prepared. We showed that the main conjugation in the binding of these drugs to BSA is hydrophobic interaction. In addition, cationic BSA (cBSA) was prepared to investigate the effect of electrostatic interaction on drug binding. The SLSA loading capacity of cBSA is significantly higher than that of BSA, this result indicates the importance of electrostatic interactions for the drug binding. Finally, we examined the competitive binding behaviors of salicylic acid, ibuprofen and aspirin to BSA. Binding sites of SL-salicylic acid and SL-ibuprofen in BSA show 96% of similarities. In addition, our results showed that binding sites of SL-salicylic acid and SL-aspirin in BSA have 73% of similarities.These results demonstrate that cw ESR spectroscopy with the spin labeling technique is an effective technique for the determination of drug-protein interactions and stoichiometric analysis of drug binding.Master Thesis Fluorescent Gold Ion Sensors: Design, Synthesis and Imaging(01. Izmir Institute of Technology, 2021) Kaya, Beraat Umur; Emrullahoğlu, MustafaOf all transition metals, gold has long sustained attention owing to its unique chemical and physical properties. Beyond that, the ease of processing gold allows its use in science, industry, and in various chemical, biological, and medical applications. For example, gold is used in medicine to treat rheumatoid arthritis, asthma, cancer, and brain and skin lesions. However, the extensive use of gold compounds can adversely impact the natural environment and biological systems due to their potential toxicity. For those reasons, identifying trace amounts of gold species in solution and cell media is crucial. Unlike the detection methods of atomic absorption spectroscopy, atomic emission spectroscopy, and inductively coupled plasma spectrometry, fluorescence-based detection methods offer easy sample preparation, rapid response, high sensitivity, reproducibility, and efficiency, all at a low cost. Today, various types of fluorescent sensors selective to gold ions have been designed, typically with BODIPY, fluorescein, rhodamine, naphthalimide, and coumarin-based fluorophores. In the work for this thesis, for the first time an enyne-derived BODIPY-based sensor was designed and synthesised to identify Au3+ ions, after which photophysical changes in the presence and absence of the analyte were examined both in solutions and in cells.Article Citation - WoS: 33Citation - Scopus: 36Epr Studies of Intermolecular Interactions and Competitive Binding of Drugs in a Drug-Bsa Binding Model(Royal Society of Chemistry, 2016) Akdoğan, Yaşar; Emrullahoğlu, Mustafa; Tatlıdil, Diğdem; Üçüncü, Muhammed; Çakan Akdoğan, GülçinUnderstanding intermolecular interactions between drugs and proteins is very important in drug delivery studies. Here, we studied different binding interactions between salicylic acid and bovine serum albumin (BSA) using electron paramagnetic resonance (EPR) spectroscopy. Salicylic acid was labeled with a stable radical (spin label) in order to monitor its mobilized (free) or immobilized (bound to BSA) states. In addition to spin labeled salicylic acid (SL-salicylic acid), its derivatives including SL-benzoic acid, SL-phenol, SL-benzene, SL-cyclohexane and SL-hexane were synthesized to reveal the effects of various drug binding interactions. EPR results of these SL-molecules showed that hydrophobic interaction is the main driving force. Whereas each of the two functional groups (-COOH and -OH) on the benzene ring has a minute but detectable effect on the drug-protein complex formation. In order to investigate the effect of electrostatic interaction on drug binding, cationic BSA (cBSA) was synthesized, altering the negative net charge of BSA to positive. The salicylic acid loading capacity of cBSA is significantly higher compared to that of BSA, indicating the importance of electrostatic interaction in drug binding. Moreover, the competitive binding properties of salicylic acid, ibuprofen and aspirin to BSA were studied. The combined EPR results of SL-salicylic acid/ibuprofen and SL-ibuprofen/salicylic acid showed that ibuprofen is able to replace up to ∼83% of bound SL-salicylic acid, and salicylic acid can replace only ∼14% of the bound SL-ibuprofen. This indicates that ∼97% of all salicylic acid and ibuprofen binding sites are shared. On the other hand, aspirin replaces only ∼23% of bound SL-salicylic acid, and salicylic acid replaces ∼50% of bound SL-aspirin, indicating that ∼73% of all salicylic acid and aspirin binding sites are shared. These results show that EPR spectroscopy in combination with the spin labeling technique is a very powerful method to investigate drug binding dynamics in detail.