Utilization of Electrospun Polystyrene Membranes as a Preliminary Step for Rapid Diagnosis
| dc.contributor.author | Işık, Tuğba | |
| dc.contributor.author | Horzum, Nesrin | |
| dc.contributor.author | Yıldız, Ümit Hakan | |
| dc.contributor.author | Liedberg, Bo | |
| dc.contributor.author | Demir, Mustafa Muammer | |
| dc.coverage.doi | 10.1002/mame.201600127 | |
| dc.date.accessioned | 2017-07-18T07:52:05Z | |
| dc.date.available | 2017-07-18T07:52:05Z | |
| dc.date.issued | 2016 | |
| dc.description.abstract | Recent advances in clinical practice drive deoxyribonucleic acid (DNA) as an important class of biomarker. Monitoring the change in their concentration suggests the initiation and/or progression of various disorders. However, low quantity of DNA biomarkers in body fluids requires a delicate isolation methodology that provides efficient separation and easy handling. This study describes a newer-generation separation technology relying on electrospun fibers of sub-micrometer diameter of a commodity polymer for DNA biomarkers in simulative serum. Fibrous polystyrene membranes are prepared by electrospinning and they are subjected to post-modification with Au. The composite membranes may provide a convenient environment for the removal of bovine serum albumin (BSA) from BSA and DNA mixtures. The eluent can be used as an efficient tool for detection of DNA biomarkers associated with diagnosis of numerous life-threatening diseases. | en_US |
| dc.description.sponsorship | FABED | en_US |
| dc.identifier.citation | Isık, T., Horzum, N., Yıldız, Ü. H., Liedberg, B., and Demir, M. M. (2016). Utilization of electrospun polystyrene membranes as a preliminary step for rapid diagnosis. Macromolecular Materials and Engineering, 301(7), 827-835. doi:10.1002/mame.201600127 | en_US |
| dc.identifier.doi | 10.1002/mame.201600127 | |
| dc.identifier.doi | 10.1002/mame.201600127 | en_US |
| dc.identifier.issn | 1438-7492 | |
| dc.identifier.issn | 1439-2054 | |
| dc.identifier.issn | 1438-7492 | |
| dc.identifier.scopus | 2-s2.0-84992312410 | |
| dc.identifier.uri | http://doi.org/10.1002/mame.201600127 | |
| dc.identifier.uri | https://hdl.handle.net/11147/5944 | |
| dc.language.iso | en | en_US |
| dc.publisher | John Wiley and Sons Inc. | en_US |
| dc.relation.ispartof | Macromolecular Materials and Engineering | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Adsorption | en_US |
| dc.subject | Bioseparations | en_US |
| dc.subject | DNA biomarkers | en_US |
| dc.subject | Electrospinning | en_US |
| dc.subject | Biomarkers | en_US |
| dc.title | Utilization of Electrospun Polystyrene Membranes as a Preliminary Step for Rapid Diagnosis | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.institutional | Işık, Tuğba | |
| gdc.author.institutional | Yıldız, Ümit Hakan | |
| gdc.author.institutional | Demir, Mustafa Muammer | |
| gdc.author.yokid | 197000 | |
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| gdc.bip.impulseclass | C5 | |
| gdc.bip.influenceclass | C5 | |
| gdc.bip.popularityclass | C5 | |
| gdc.coar.access | open access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.collaboration.industrial | false | |
| gdc.description.department | İzmir Institute of Technology. Materials Science and Engineering | en_US |
| gdc.description.endpage | 835 | en_US |
| gdc.description.issue | 7 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q1 | |
| gdc.description.startpage | 827 | en_US |
| gdc.description.volume | 301 | en_US |
| gdc.description.wosquality | Q2 | |
| gdc.identifier.openalex | W2346386341 | |
| gdc.identifier.wos | WOS:000379939000006 | |
| gdc.index.type | WoS | |
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| gdc.oaire.keywords | Bioseparations | |
| gdc.oaire.keywords | DNA biomarkers | |
| gdc.oaire.keywords | Electrospinning | |
| gdc.oaire.keywords | Adsorption | |
| gdc.oaire.keywords | Biomarkers | |
| gdc.oaire.popularity | 3.3765586E-9 | |
| gdc.oaire.publicfunded | false | |
| gdc.oaire.sciencefields | 02 engineering and technology | |
| gdc.oaire.sciencefields | 0210 nano-technology | |
| gdc.oaire.sciencefields | 01 natural sciences | |
| gdc.oaire.sciencefields | 0104 chemical sciences | |
| gdc.openalex.collaboration | International | |
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