Synthesis of Stilbene-Fused 2'-hydroxychalcones and Flavanones
| dc.contributor.author | Akçok, İsmail | |
| dc.contributor.author | Çağır, Ali | |
| dc.coverage.doi | 10.1016/j.bioorg.2010.04.001 | |
| dc.date.accessioned | 2016-12-27T12:35:16Z | |
| dc.date.available | 2016-12-27T12:35:16Z | |
| dc.date.issued | 2010 | |
| dc.description.abstract | Synthesis of stilbene-fused chalcones and flavanones were successfully completed. Molecules were designed in a way to mimic the structural features of both "stilbene and chalcones" or "stilbene and flavanones" at the same time, and synthesized by three steps. Heck reactions of 3-bromobenzaldehyde with styrene derivatives gave corresponding (E)-stilbenes, which were reacted with acetophenones to furnish stilbene-fused 2′-hydroxychalcones under basic conditions. Finally, intramolecular cyclization reactions were performed to produce stilbene-fused flavanones. © 2010 Elsevier Inc. | en_US |
| dc.description.sponsorship | DPT Research Grant DPT-2003K120690 (DPT10) | en_US |
| dc.identifier.citation | Akçok, İ., and Çağır, A. (2010). Synthesis of stilbene-fused 2′-hydroxychalcones and flavanones. Bioorganic Chemistry, 38(4), 139-143. doi:10.1016/j.bioorg.2010.04.001 | en_US |
| dc.identifier.doi | 10.1016/j.bioorg.2010.04.001 | |
| dc.identifier.doi | 10.1016/j.bioorg.2010.04.001 | en_US |
| dc.identifier.issn | 0045-2068 | |
| dc.identifier.scopus | 2-s2.0-77954212534 | |
| dc.identifier.uri | http://doi.org/10.1016/j.bioorg.2010.04.001 | |
| dc.identifier.uri | https://hdl.handle.net/11147/2685 | |
| dc.language.iso | en | en_US |
| dc.publisher | Elsevier Ltd. | en_US |
| dc.relation.ispartof | Bioorganic Chemistry | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Chalcone | en_US |
| dc.subject | Flavanone | en_US |
| dc.subject | Heck reaction | en_US |
| dc.subject | Michael addition | en_US |
| dc.subject | Stilbene | en_US |
| dc.title | Synthesis of Stilbene-Fused 2'-hydroxychalcones and Flavanones | en_US |
| dc.type | Article | en_US |
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| gdc.author.institutional | Akçok, İsmail | |
| gdc.author.institutional | Çağır, Ali | |
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| gdc.description.department | İzmir Institute of Technology. Chemistry | en_US |
| gdc.description.endpage | 143 | en_US |
| gdc.description.issue | 4 | en_US |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
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| gdc.description.startpage | 139 | en_US |
| gdc.description.volume | 38 | en_US |
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| gdc.identifier.pmid | 20457464 | |
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| gdc.oaire.keywords | Heck reaction | |
| gdc.oaire.keywords | Chalcone | |
| gdc.oaire.keywords | Chalcones | |
| gdc.oaire.keywords | Cyclization | |
| gdc.oaire.keywords | Michael addition | |
| gdc.oaire.keywords | Stilbene | |
| gdc.oaire.keywords | Flavanones | |
| gdc.oaire.keywords | Stilbenes | |
| gdc.oaire.keywords | Flavanone | |
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