A New Fluorescent 'turn On' Probe for Rapid Detection of Biothiols

dc.contributor.author Üçüncü, Muhammed
dc.contributor.author Zeybek, Hüseyin
dc.contributor.author Karakuş, Erman
dc.contributor.author Üçüncü, Canan
dc.contributor.author Emrullahoğlu, Mustafa
dc.date.accessioned 2021-12-02T18:16:11Z
dc.date.available 2021-12-02T18:16:11Z
dc.date.issued 2020
dc.description.abstract We designed and synthesised a novel molecular probe exhibiting high selectivity and sensitivity towards reactive sulphur species (RSS) over other amino acids and biologically relevant species, as well as scrutinised its spectroscopic behaviours under physiological conditions and in living milieu. We used an electrophilic cyanate group as a masking agent to block the excited state intramolecular proton transfer process of 2-(2-cyanato-3-methoxyphenyl)benzo[d]thiazole (HMBT-OCN), which readily hydrolyses to the highly fluorescent structure, 2-(2'-Hydroxy-3'-methoxyphenyl) benzothiazole (HMBT-OH), in the presence of reactive sulphur species. [GRAPHICS] . en_US
dc.description.sponsorship The authors gratefully acknowledge IZTECH (zmir Institute of Technology) for financial support. en_US
dc.identifier.doi 10.1080/10610278.2021.1893321
dc.identifier.issn 1061-0278
dc.identifier.issn 1029-0478
dc.identifier.scopus 2-s2.0-85101736128
dc.identifier.uri https://doi.org/10.1080/10610278.2021.1893321
dc.identifier.uri https://hdl.handle.net/11147/11788
dc.language.iso en en_US
dc.publisher Taylor and Francis Ltd. en_US
dc.relation.ispartof Supramolecular Chemistry en_US
dc.rights info:eu-repo/semantics/closedAccess en_US
dc.subject Biothiols en_US
dc.subject ESIPT en_US
dc.subject Electrophilic cyanate en_US
dc.subject Cell imaging en_US
dc.title A New Fluorescent 'turn On' Probe for Rapid Detection of Biothiols en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.id 0000-0002-8221-2597
gdc.author.id 0000-0002-8221-2597 en_US
gdc.author.institutional Zeybek, Hüseyin
gdc.author.institutional Üçüncü, Canan
gdc.author.institutional Emrullahoğlu, Mustafa
gdc.author.wosid Karakus, Erman/AAW-9784-2021
gdc.author.wosid Emrullahoglu, Mustafa/AAJ-7190-2021
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gdc.coar.access metadata only access
gdc.coar.type text::journal::journal article
gdc.collaboration.industrial false
gdc.description.department İzmir Institute of Technology. Chemistry en_US
gdc.description.department İzmir Institute of Technology. Photonics en_US
gdc.description.endpage 641 en_US
gdc.description.issue 12 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q3
gdc.description.startpage 634 en_US
gdc.description.volume 32 en_US
gdc.description.wosquality Q2
gdc.identifier.openalex W3135755125
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gdc.oaire.sciencefields 01 natural sciences
gdc.oaire.sciencefields 0104 chemical sciences
gdc.openalex.collaboration National
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gdc.opencitations.count 2
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