Complex Coacervation of Silk Fibroin and Hyaluronic Acid

dc.contributor.author Malay, Özge
dc.contributor.author Bayraktar, Oğuz
dc.contributor.author Batıgün, Ayşegül
dc.coverage.doi 10.1016/j.ijbiomac.2006.09.017
dc.date.accessioned 2016-10-18T13:34:51Z
dc.date.available 2016-10-18T13:34:51Z
dc.date.issued 2007
dc.description.abstract This study aimed to investigate the pH-induced complexation of silk fibroin (SF) and hyaluronic acid (HA). SF-HA complex coacervation was investigated by monitoring turbidity of the SF-HA system under slow acidification. Gravimetric analysis was performed to determine the yield of complex coacervation and viscosity of the system was measured to study the formation of the complexes at different pH values. The influences of total biopolymer concentration and biopolymer weight ratio on complex coacervation were examined during the analyses. Formation of the complexes was evidenced by the minimum viscosity and the maximum turbidity observed in the system. SF-HA complexes were formed within the pH-window of 2.5-3.5 regardless of the total biopolymer concentration or biopolymer ratio. Complex coacervation of SF-HA showed a reversible behavior and coacervation could be handled even in excess amounts of the biopolymers, which pointed out a non-stoichiometric complexation. en_US
dc.description.sponsorship İzmir Institute of Technology en_US
dc.identifier.citation Malay, Ö., Bayraktar, O., and Batıgün, A. (2007). Complex coacervation of silk fibroin and hyaluronic acid. International Journal of Biological Macromolecules, 40(4), 387-393. doi:10.1016/j.ijbiomac.2006.09.017 en_US
dc.identifier.doi 10.1016/j.ijbiomac.2006.09.017 en_US
dc.identifier.doi 10.1016/j.ijbiomac.2006.09.017
dc.identifier.issn 0141-8130
dc.identifier.issn 1879-0003
dc.identifier.scopus 2-s2.0-33846950077
dc.identifier.uri http://doi.org/10.1016/j.ijbiomac.2006.09.017
dc.identifier.uri https://hdl.handle.net/11147/2273
dc.language.iso en en_US
dc.publisher Elsevier Ltd. en_US
dc.relation.ispartof International Journal of Biological Macromolecules en_US
dc.rights info:eu-repo/semantics/openAccess en_US
dc.subject Complex coacervation en_US
dc.subject Hyaluronic acid en_US
dc.subject Protein-polysaccharide interactions en_US
dc.subject Silk fibroin en_US
dc.title Complex Coacervation of Silk Fibroin and Hyaluronic Acid en_US
dc.type Article en_US
dspace.entity.type Publication
gdc.author.institutional Malay, Özge
gdc.author.institutional Bayraktar, Oğuz
gdc.author.institutional Batıgün, Ayşegül
gdc.author.yokid 131394
gdc.bip.impulseclass C4
gdc.bip.influenceclass C4
gdc.bip.popularityclass C4
gdc.coar.access open access
gdc.coar.type text::journal::journal article
gdc.collaboration.industrial false
gdc.description.department İzmir Institute of Technology. Chemical Engineering en_US
gdc.description.endpage 393 en_US
gdc.description.issue 4 en_US
gdc.description.publicationcategory Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı en_US
gdc.description.scopusquality Q1
gdc.description.startpage 387 en_US
gdc.description.volume 40 en_US
gdc.description.wosquality Q1
gdc.identifier.openalex W2015970551
gdc.identifier.pmid 17101174
gdc.identifier.wos WOS:000245070000014
gdc.index.type WoS
gdc.index.type Scopus
gdc.index.type PubMed
gdc.oaire.accesstype BRONZE
gdc.oaire.diamondjournal false
gdc.oaire.impulse 15.0
gdc.oaire.influence 5.5466547E-9
gdc.oaire.isgreen true
gdc.oaire.keywords Electrophoresis
gdc.oaire.keywords Viscosity
gdc.oaire.keywords Hyaluronic acid
gdc.oaire.keywords Silk
gdc.oaire.keywords Titrimetry
gdc.oaire.keywords Silk fibroin
gdc.oaire.keywords Hydrogen-Ion Concentration
gdc.oaire.keywords Biopolymers
gdc.oaire.keywords Solubility
gdc.oaire.keywords Nephelometry and Turbidimetry
gdc.oaire.keywords Complex coacervation
gdc.oaire.keywords Animals
gdc.oaire.keywords Protein-polysaccharide interactions
gdc.oaire.keywords Hyaluronic Acid
gdc.oaire.keywords Fibroins
gdc.oaire.popularity 1.4505351E-8
gdc.oaire.publicfunded false
gdc.oaire.sciencefields 0301 basic medicine
gdc.oaire.sciencefields 02 engineering and technology
gdc.oaire.sciencefields 03 medical and health sciences
gdc.oaire.sciencefields 0210 nano-technology
gdc.openalex.collaboration National
gdc.openalex.fwci 1.61425341
gdc.openalex.normalizedpercentile 0.83
gdc.opencitations.count 65
gdc.plumx.crossrefcites 46
gdc.plumx.mendeley 93
gdc.plumx.scopuscites 70
gdc.scopus.citedcount 70
gdc.wos.citedcount 68
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