Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collection
Permanent URI for this collectionhttps://hdl.handle.net/11147/7148
Browse
20 results
Search Results
Now showing 1 - 10 of 20
Article Citation - WoS: 2Citation - Scopus: 2A New Fluorescent 'turn On' Probe for Rapid Detection of Biothiols(Taylor and Francis Ltd., 2020) Üçüncü, Muhammed; Zeybek, Hüseyin; Karakuş, Erman; Üçüncü, Canan; Emrullahoğlu, MustafaWe designed and synthesised a novel molecular probe exhibiting high selectivity and sensitivity towards reactive sulphur species (RSS) over other amino acids and biologically relevant species, as well as scrutinised its spectroscopic behaviours under physiological conditions and in living milieu. We used an electrophilic cyanate group as a masking agent to block the excited state intramolecular proton transfer process of 2-(2-cyanato-3-methoxyphenyl)benzo[d]thiazole (HMBT-OCN), which readily hydrolyses to the highly fluorescent structure, 2-(2'-Hydroxy-3'-methoxyphenyl) benzothiazole (HMBT-OH), in the presence of reactive sulphur species. [GRAPHICS] .Article Citation - WoS: 23Citation - Scopus: 23Bodipy-Vinyl Dibromides as Triplet Sensitisers for Photodynamic Therapy and Triplet-Triplet Annihilation Upconversion(Royal Society of Chemistry, 2021) Dartar, Suay; Üçüncü, Muhammed; Karakuş, Erman; Hou, Yuqi; Zhao, Jianzhang; Emrullahoğlu, MustafaWe devised a new generation of halogen-based triplet sensitisers comprising geminal dibromides at the vinyl backbone of a BODIPY fluorophore. Incorporating geminal dibromides into the pi-conjugation of BODIPY enhanced intersystem crossing due to the heavy atom effect, which in turn improved the extent of excited triplet states.Article Citation - WoS: 22Citation - Scopus: 22Fluorescein Propiolate: a Propiolate- Decorated Fluorescent Probe With Remarkable Selectivity Towards Cysteine(Royal Society of Chemistry, 2019) Karakuş, Erman; Sayar, Melike; Dartar, Suay; Kaya, Beraat Umur; Emrullahoğlu, MustafaA fluorescent probe decorated with an alkynyl ester unit (e.g. propiolate) displayed a selective turn-on type fluorescent response towards cysteine. Following a sequential addition-cyclisation pathway mediated by the addition of cysteine, the pre-fluorescent dye rapidly transformed into a new structure and induced a fluorescent response clearly observable with the naked eye.Article Citation - WoS: 56Citation - Scopus: 55A Bodipy-Based Fluorescent Probe To Visually Detect Phosgene: Toward the Development of a Handheld Phosgene Detector(John Wiley and Sons Inc., 2018) Sayar, Melike; Karakuş, Erman; Güner, Tuğrul; Yıldız, Büşra; Yıldız, Ümit Hakan; Emrullahoğlu, MustafaA boron-dipyrromethene (BODIPY)-based fluorescent probe with a phosgene-specific reactive motif shows remarkable selectivity toward phosgene, in the presence of which the nonfluorescent dye rapidly transforms into a new structure and induces a fluorescent response clearly observable to the naked eye under ultraviolet light. Given that dynamic, a prototypical handheld phosgene detector with a promising sensing capability that expedites the detection of gaseous phosgene without sophisticated instrumentation was developed. The proposed method using the handheld detector involves a rapid response period suitable for issuing early warnings during emergency situations.Article Citation - WoS: 5Citation - Scopus: 6Determination of Force-Free Wet Adhesion of Mussel-Inspired Polymers To Spin Labeled Surface(Elsevier, 2017) Kırpat, İklima; Göksel, Yaman; Karakuş, Erman; Emrullahoğlu, Mustafa; Akdoğan, YaşarHydration repulsive forces oppose the adhesive interactions, especially in the force-free conditions. Here, we studied spontaneous wet adhesion of 3,4-dihydroxyphenylalanine (DOPA) functionalized poly(ethylene glycol) (PEG) polymers inspired by marine mussels. Using electron paramagnetic resonance (EPR) spectroscopy, we can monitor spontaneous adhesion of DOPA containing polymer to suspended spin labeled hydrophobic polystyrene nanobeads at molecular level. The surface coverage up to 82% is obtained from EPR measurements. However, in the force-free condition, EPR measurements do not show any detectable DOPA based adhesion to hydrophilic silica nanobead.Article Citation - WoS: 51Citation - Scopus: 53Bodipy-Au(i): a Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy(American Chemical Society, 2017) Üçüncü, Muhammed; Karakuş, Erman; Kurulgan Demirci, Eylem; Sayar, Melike; Dartar, Suay; Emrullahoğlu, MustafaUpon complexation with Au(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (φδ = 0.84), the new BODIPY-Au(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC50 = 2.5 nM).Article Citation - WoS: 80Citation - Scopus: 82Electrophilic Cyanate as a Recognition Motif for Reactive Sulfur Species: Selective Fluorescence Detection of H2s(American Chemical Society, 2016) Karakuş, Erman; Üçüncü, Muhammed; Emrullahoğlu, MustafaAn ESIPT-based fluorescent dye, 3-hydroxyflavone, is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe for cellular sulfur species. This novel probe structure, displays an extremely fast, highly sensitive and selective "turn-on" type fluorescent response toward H2S. We have also documented its utility for imaging of H2S in the living cells.Article Citation - WoS: 22Citation - Scopus: 24A Fluorescein-Based Chemodosimeter for Selective Gold(iii) Ion Monitoring in Aqueous Media and Living Systems(Elsevier Ltd., 2016) Çetintaş, Ceyla; Karakuş, Erman; Üçüncü, Muhammed; Emrullahoğlu, MustafaWe constructed a turn-on type chemodosimeter based upon a fluorescein scaffold for the rapid, selective detection of gold(III) ions over other metal species. This novel probe structure offers distinct features including high water solubility, a low detection limit, rapid response time and applicability in imaging gold(III) ions in living cells.Article Citation - WoS: 22Citation - Scopus: 23A Guanidinium Modified Rhodamine-Based Fluorescent Probe for in Vitro/Vivo Imaging of Gold Ions(Royal Society of Chemistry, 2015) Karakuş, Erman; Çakan Akdoğan, Gülçin; Emrullahoğlu, MustafaWe devised a rhodamine-based fluorescent probe functionalized with a guanidinium moiety, which both operates efficiently in pure aqueous media and displays a selective fluorescence response to Au3+ ions. We also demonstrated the successful fluorescence imaging of Au3+ within living cells and a vertebrate species, the zebrafish.Article Citation - WoS: 36Citation - Scopus: 37A Bodipy-Based Fluorescent Probe for Ratiometric Detection of Gold Ions: Utilization Of: Z -Enynol as the Reactive Unit(Royal Society of Chemistry, 2016) Üçüncü, Muhammed; Karakuş, Erman; Emrullahoğlu, MustafaUsing an irreversible intramolecular cyclisation pathway triggered by gold ions, a boron-dipyrromethene (BODIPY) based fluorescent probe integrated with a reactive Z-enynol motif responds selectively to gold ions. With the addition of gold(iii), the probe displays ratiometric fluorescence behaviour clearly observable to the naked eye under both visible and UV light. © The Royal Society of Chemistry 2016.