Bodipy-Au(i): a Photosensitizer for Singlet Oxygen Generation and Photodynamic Therapy
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Authors
Dartar, Suay
Emrullahoğlu, Mustafa
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BRONZE
Green Open Access
Yes
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No
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Top 10%
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Abstract
Upon complexation with Au(I), a photoinactive BODIPY derivative was transformed into a highly photoactive triplet sensitizer. Along with high efficiency in singlet oxygen generation (φδ = 0.84), the new BODIPY-Au(I) skeleton showed excellent photocytotoxic activity against cancer cell lines (EC50 = 2.5 nM).
Description
Keywords
BODIPY, Cancer cell, Photodynamic therapy, Photosensitizer, Boron Compounds, Photosensitizing Agents, Molecular Structure, Photochemotherapy, Singlet Oxygen, BODIPY, Cancer cell, Photosensitizer, Photodynamic therapy
Fields of Science
01 natural sciences, 0104 chemical sciences
Citation
Üçüncü, M., Karakuş, E., Kurulgan Demirci, E., Sayar, M., Dartar, S., and Emrullahoğlu, M. (2017). BODIPY-Au(I): A photosensitizer for singlet oxygen generation and photodynamic therapy. Organic Letters, 19(10), 2522-2525. doi:10.1021/acs.orglett.7b00791
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OpenCitations Citation Count
53
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Volume
19
Issue
10
Start Page
2522
End Page
2525
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Scopus : 53
PubMed : 8
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