A Rare ?-Pyranopyrazole Skeleton: Design, One-Pot Synthesis and Computational Study

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HYBRID

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Yes

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4

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3

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Abstract

Drawing upon a consecutive amide coupling and intramolecular cyclisation pathway, a one-pot, straightforward synthetic route has been developed for a range of pyrazole fused γ-pyrone derivatives. The reaction mechanism proposed for the chemoselective formation of γ-pyranopyrazole is furthermore fully supported by experimental and computational studies. © The Royal Society of Chemistry 2016.

Description

Keywords

Positive ions, Pyrazoles, Amide couplings, Reaction mechanism, Positive ions, Pyrazoles, Reaction mechanism, Amide couplings

Fields of Science

01 natural sciences, 0104 chemical sciences

Citation

Üçüncü, M. Cantürk, C., Karakuş, E., Zeybek, H., Bozkaya, U., Soydaş, E., Şahin, E., and Emrullahoğlu, M. (2016). A rare γ-pyranopyrazole skeleton: Design, one-pot synthesis and computational study. Organic and Biomolecular Chemistry, 14/31), 7490-7494. doi:10.1039/c6ob01099g

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4

Volume

14

Issue

31

Start Page

7490

End Page

7494
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