Gold(i)/Zn(ii) Catalyzed Tandem Hydroamination/Annulation Reaction of 4-Yne

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BRONZE

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Yes

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Abstract

The tandem hydroamination-annulation reaction of 4-pentyne-nitriles in the presence of amine nucleophiles and a cooperatively operating catalyst system, consisting of Ph3PAuCl and Zn(ClO4)2, provides an efficient route to 2-aminopyrroles. Two regioisomeric 2-aminopyrroles were formed in moderate to good yields. © 2010 The Royal Society of Chemistry.

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Fields of Science

01 natural sciences, 0104 chemical sciences

Citation

Demir, A. S., Emrullahoğlu, M., and Buran, K. (2010). Gold(i)/Zn(ii) catalyzed tandem hydroamination/annulation reaction of 4-yne-nitriles. Chemical Communications, 46(42), 8032-8034. doi:10.1039/c0cc02357d

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Q2

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Q2
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OpenCitations Citation Count
61

Source

Chemical Communications

Volume

46

Issue

42

Start Page

8032

End Page

8034
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